This Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program provides $320,861 to the University of Washington to develop tools and investigate the biocompatibility of expanded genetic alphabets containing non-standard DNA bases. The research aims to improve the accuracy and generalizability of next-generation DNA sequencing for these unnatural base pairs, develop new methods to measure polymerase replication fidelity, and assess the...
The University of Washington was awarded a $317,972 Project Grant from the National Science Foundation Division of Biological Infrastructure under the Computer and Information Science and Engineering federal grant program (CFDA 47.070). The two-year grant will support collaborative research and integrated modeling of the Caenorhabditis elegans nervous system. Specifically, the University will conduct comprehensive electrophysiological recording of the nematode's nervous system to develop a...
The University of Washington was awarded a two-year, $165,949 Project Grant from the National Science Foundation under the Computer and Information Science and Engineering federal grant program (CFDA 47.070). The grant will support collaborative research on natural language (variety) processing from October 1, 2021 to September 30, 2023. The Computer and Information Science and Engineering program aims to advance computing and communication sciences and technologies through...
This federal Project Grant award of $500,408 from the National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems supports collaborative research between Northwestern University and the University of Washington from September 2021 through August 2024. The research aims to engineer MS2 bacteriophage capsid assembly using systematic fitness landscapes, as described in the NSF Directorate for Engineering program. This program seeks to improve quality of...
This $1,999,998 National Science Foundation Project Grant, funded under the Biological Sciences program (CFDA 47.074), supports research at the University of Washington to advance plant synthetic biology through deciphering the grammar of crop gene regulatory elements. The three-year award beginning March 1, 2023 will apply massively parallel reporter assays and machine learning to characterize tens of thousands of genetic regulatory elements in maize and tomato, including enhancers,...
The University of Washington was awarded a $335,005 Project Grant from the National Science Foundation Division of Integrative Organismal Systems. The grant supports the research project "COLLABORATIVE RESEARCH: RUI: IMPLICATIONS OF BACTERIALLY DRIVEN CROSS-KINGDOM CHEMICAL INTERACTIONS" from May 15, 2021 through April 30, 2024. The grant funds basic research to increase scientific understanding of major problems in biological sciences, as described in the Biological Sciences program...
This $1,120,000 Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) aims to explore the boundaries of life's genetic alphabet beyond the natural 4-letter system (A, T, G, C). The research will develop model systems to study the biomolecular properties of a 6-letter genetic alphabet (A, T, G, C, P, Z) and map critical interactions necessary for translation of this expanded genetic code. The project will use synthetic biology and chemical...
The University of Washington was awarded a three-year, $599,995 Project Grant from the National Science Foundation Division of Computer and Network Systems under the Computer and Information Science and Engineering program (CFDA 47.070). The grant will support research titled "COLLABORATIVE RESEARCH: CNS CORE: MEDIUM: RECONFIGURABLE KERNEL DATAPATHS WITH ADAPTIVE OPTIMIZATIONS" to be conducted between October 1, 2021 and September 30, 2024. Specifically, the University will investigate...
The University of Washington was awarded a three-year $450,000 Project Grant from the National Science Foundation's Division of Chemistry. The grant falls under the Mathematical and Physical Sciences program (CFDA 47.049), which aims to advance scientific knowledge and understanding in these fields. Through this funding, the University will conduct research from July 2021 through June 2024 to test the p53 gene regulation code using chemical protein synthesis. The project seeks to gain new...
The University of Washington was awarded a $500,000 Project Grant from the National Science Foundation Division of Computer and Network Systems under the Computer and Information Science and Engineering federal grant program (CFDA 47.070). The three-year award will support the University's efforts to evolve the Defects4J benchmark and infrastructure to enable sustained innovation and reproducibility in software engineering research. Specifically, the University will work to enhance Defects4J, an...