The National Science Foundation awarded American University a $1,088,636 project grant under the Biological Sciences program (CFDA 47.074) to conduct collaborative research on targeted neurosteroidogenesis and complex memory function from June 2021 through May 2025. The grant supports research to advance understanding of major problems in the biological sciences by investigating how specific neurosteroid hormones impact complex memory processes. The funding enables American University...
The National Science Foundation (NSF) awarded a $502,981 Project Grant under the Biological Sciences (CFDA 47.074) program to the University of Richmond. The grant, spanning March 1, 2025 to February 29, 2028, will fund research to advance the understanding of how neurons populate their membranes with AMPA receptors, a process essential for memory formation. The project will investigate the regulation of membrane fusion during AMPA receptor delivery, with a focus on identifying novel proteins...
The National Science Foundation (NSF) awarded a $253,890 Project Grant under the Biological Sciences program (CFDA 47.074) to Western University of Health Sciences to conduct research on sensory membrane proteins. The goal is to develop computational tools capable of realistic simulations of how these proteins respond to external stimuli like pressure, heat, and sound. The research project, titled "Collaborative Research: Ultra-Fast Simulations of Sensory Membrane Proteins with Validation...
This $550,000 Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research at Georgetown University to understand how the extracellular matrix regulates synaptic stability and function in the brain. The project aims to elucidate the mechanisms by which matrix metalloproteinases dynamically modulate the extracellular environment to maintain the balance between synapse adaptability and stability, which is critical for healthy brain...
This $250,000 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research by the New Jersey Institute of Technology (NJIT) to investigate the role of neuromodulators in regulating the activity and plasticity of neuronal networks. The research aims to elucidate the mechanisms by which neuromodulators constrain the parameter space of neuronal activity, both in response to perturbations and over long time scales. The project utilizes the...
This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research at Carleton College that will investigate how neurons develop and form circuits that regulate reproductive behaviors in the model organism C. elegans. The $419,182 award, effective September 1, 2024 through August 31, 2027, aims to elucidate the molecular mechanisms that integrate sex-determining signals with neurodevelopmental processes. The research will leverage...
The National Science Foundation (NSF) awarded a $208,090 Project Grant to Purdue University under the Social, Behavioral, and Economic Sciences (CFDA 47.075) program. The grant is for a 3-year project from August 2024 to July 2027 focused on building a conceptual framework for understanding the "engram" - the neural mechanisms underlying memory retention and recall. The project will employ methods from biology, history, and philosophy of science to develop an updated, expanded...
This $495,341 Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports research at Smith College to investigate the G protein-coupled receptor GPR37 and its role in regulating the maturation of new neurons in the adult hippocampus. The project aims to build on preliminary findings that suggest GPR37 may potentiate Wnt signaling to positively influence the integration of newborn neurons into established brain circuits. Key aspects of...
The National Science Foundation awarded a $138,000 Project Grant to support research titled "The Social Brain: Behavioral, Neural, and Transcriptomic Modulation of the Brain" from July 1, 2021 to June 30, 2023. This funding was provided under the Biological Sciences program (CFDA 47.074) to promote progress in the biological sciences and increase understanding of major issues facing the nation. Over the two year period of performance in Columbia, Missouri, this award will allow the...
This $185,440 Project Grant awarded by the National Science Foundation's (NSF) Mathematical and Physical Sciences Program (CFDA 47.049) will support research by the Salk Institute for Biological Studies to study the low-dimensional neural activity manifolds that underlie brain function. The project aims to characterize the curvature and dimensionality of these manifolds and examine how they change with learning. Additionally, the researchers will work to generalize classic results on the...