This National Science Foundation (NSF) Project Grant award under the Engineering program (CFDA 47.041) supports basic research to uncover the mechanisms by which mechanical forces at the protein level regulate cell mechanics and direct tissue-scale behaviors. The $616,151 award, with a project period from September 1, 2024 to August 31, 2027, will fund an interdisciplinary study leveraging molecular biology, bioengineering, materials science, and computational approaches. The research will...
The National Science Foundation awarded a $200,000 Project Grant to Utah State University under the Engineering program (CFDA 47.041) from February 1, 2022 to January 31, 2024. The grant funds research to develop constitutive equations of chemo-mechanics through atomistic simulations. As part of its mission to foster innovation and excellence in engineering research, the NSF Engineering program supports fundamental research that advances understanding of engineering systems and improves the...
This $297,984 federal Project Grant, awarded on February 1, 2025 by the National Science Foundation's (NSF) Engineering program (CFDA 47.041), supports research to quantify the mechanical forces inside living cells and determine how changes in these forces impact cell behavior. The goal is to develop predictive mechanobiotechnology approaches to control cell function through the application of external mechanical forces. The research team at the University of Texas Health Science Center at...
The National Science Foundation awarded a $890,510 project grant to Virginia Commonwealth University under the Engineering federal grant program (CFDA 47.041) for research titled "BIOMECHANICS OF LEADER CELLS." The five-year award, issued February 1, 2022 with a completion date of January 31, 2027, will support research into the biomechanics of leader cells. The NSF's Engineering program seeks to improve quality of life and economic strength by fostering innovation and excellence in...
This National Science Foundation (NSF) Project Grant award under the Engineering (CFDA 47.041) program provides $314,769 to the University of Delaware to conduct research that aims to advance the fundamental understanding of how cells and tissues communicate information about their mechanical environment. The research project will develop new material platforms based on magnetic materials that can locally and dynamically change their stiffness to mimic biological events like tissue injury or...
The National Science Foundation (NSF) Engineering program awarded a $377,755 Project Grant to the University of New Haven, Incorporated to support fundamental research on the mechanoregulation of collective cell migration in biomimetic microenvironments. This 3-year grant, effective from September 1, 2024 to August 31, 2027, will enable the University of New Haven to investigate how mechanical forces and biochemical factors interact to regulate collective cell migration, a crucial process in...
This National Science Foundation (NSF) Engineering Research Initiation (ERI) award, under CFDA 47.041, will fund research at Wesleyan University to investigate the principles governing interactions at the interface between different groups of cells. The $199,982 project, spanning July 2025 to June 2027, aims to understand how cells from distinct tissues organize and interact when they come into contact, which is crucial for processes like tissue development, wound healing, and cancer metastasis....
This National Science Foundation Project Grant award of $937,018 provides funding for collaborative nanoscience research between the University of Texas at El Paso and Baylor College of Medicine. The award is made under the NSF Engineering Directorate's 47.041 CFDA program to support innovation and excellence in engineering research. Specifically, the researchers will investigate the influence of physical and chemical factors of nanomaterials on cell adhesion, protein synthesis, and cellular...
The National Science Foundation (NSF) awarded a $646,451 Project Grant under its Engineering (CFDA 47.041) program to The Regents of the University of Colorado, doing business as the University of Colorado, to research how the mechanical properties of the extracellular matrix regulate neutrophil function. The 5-year project, which began on June 1, 2025, aims to define how matrix modulus, viscoelasticity, and dynamic tissue stiffening influence neutrophil behavior during inflammation. This...
This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $389,397 to Michigan State University (MSU) to conduct research characterizing the strain rate-dependent mechanical behavior of cell-cell adhesions. The key objectives are to: 1) examine the rate-dependent stress relaxation and tensioning of the cell adhesion-cytoskeleton network, and 2) examine the rate-dependent enhancement of cell-cell junctions that reduces rupture potential under...