Project Grant 2042117
- The National Science Foundation awarded a $299,990 project grant to Cleveland State University under the Engineering program (CFDA 47.041) for research titled "COLLABORATIVE RESEARCH: GLIAL SCAR MORPHOLOGY INFORMED TUNABLE BIOMIMETIC PLATFORMS TOWARD SPINAL CORD INJURY REPAIR." The three-year award beginning June 1, 2021 will support Cleveland State University's research efforts to develop biomimetic platforms informed by glial scar morphology to advance repair of spinal cord injuries....
- The University of Akron received a $748,267 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to conduct research on spinal cord injury (SCI) regeneration and recovery. The three-year research project, starting on August 15, 2023, will explore the use of tandem cell replacement and chondroitin sulfate proteoglycan (CSPG) inhibition techniques to promote SCI regeneration and recovery. The University of Akron has a strong...
- This three-year, $598,468 project grant from the National Science Foundation's Engineering Directorate (CFDA 47.041) will support research at Rowan University to improve understanding of astrocyte mechanobiology following central nervous system injury. The grantee will use magnetically active hydrogels to interrogate how dynamically changing tissue stiffness affects astrocyte contribution to glial scar formation after spinal cord injury. Experiments will characterize mechanical property...
- This $425,167 National Science Foundation (NSF) Engineering (CFDA 47.041) award to The Research Foundation for the State University of New York supports the development of a novel multifunctional soft neural probe technology. The goal is to use this new device to study the pathophysiology of spinal cord injuries and explore approaches to promote functional recovery. The award will fund the creation of soft polymer-based probes capable of optical stimulation, electrical recording, drug...
- This Project Grant awarded by the National Science Foundation (CFDA 47.041 - Engineering) to Cleveland State University (CSU) provides $500,000 in funding from January 1, 2025 to December 31, 2027 to develop bioprinted tissue scaffolds with Schwann cell density gradients and electrical conductivity for peripheral nerve regeneration. The goal is to understand how Schwann cell density gradients and electrical properties within the scaffolds can enhance the regeneration of injured peripheral...
- This Project Grant award, valued at $531,543 and funded by the National Science Foundation's Engineering program (CFDA 47.041), aims to develop innovative soft and stretchable hydrogel electrodes for restoring motor function in individuals with spinal cord injuries. The key research objectives include: (1) developing biocompatible hydrogel materials with excellent electrical performance for neural interfaces, (2) designing minimally invasive electrodes that can be injected to precisely...
- This Project Grant award from the National Science Foundation (NSF), under the Engineering program (CFDA 47.041), provides $200,000 to Cleveland State University to investigate scaffold degradation for peripheral nerve regeneration. The goal is to develop better ways to control scaffold degradation in order to more effectively support nerve repair and healing. The research will utilize 3D bioprinting to create scaffolds with precise structures and study how scaffold breakdown affects nerve...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $274,976 to Ecate LLC aims to develop a novel intraspinal stimulator system to restore sensation and volitional motor control in spinal cord injury patients. The project will fabricate nanopatterned stimulating electrodes coupled with custom CMOS chips to deliver spatially selective electrical stimulation to the spinal cord. This closed-loop neural interface system is intended...
- The National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853), awarded a $184,837 Project Grant to The Ohio State University on April 25, 2025. The grant supports research on promoting spinal cord repair using a polymer-based drug delivery system. The project aims to investigate the use of targeted intraspinal delivery of gabapentinoids, a class of drugs that can promote axon...
- This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) will support research to study how astrocytes, a critical cell type in the brain, respond to mechanical forces and strain associated with traumatic brain injury (TBI). The $705,806 award to Tufts University will fund the development of controlled 3D brain-like cell culture environments and ex vivo brain cultures to quantify astrocytes' acute and chronic responses to mechanical perturbation...
The University of Akron will conduct collaborative research on glial scar morphology to develop tunable biomimetic platforms for spinal cord injury repair under a $306,999 National Science Foundation project grant awarded June 1, 2021 through the Engineering program (CFDA 47.041). The three-year award will support research exploring glial scar tissue formation after spinal cord damage and applying those insights to create customizable synthetic platforms that mimic the natural extracellular environment to promote repair. By gaining a deeper understanding of the cellular and molecular mechanisms governing scar formation, the researchers aim to design biomaterials better able to facilitate regeneration and functional recovery following spinal cord injury. The place of performance is The University of Akron in Akron, Ohio. The NSF Directorate for Engineering seeks to advance innovation and excellence in engineering research and education to improve lives and economic strength.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $7.0k | 7/12/22 | ||
| Not listed | $300.0k | 5/17/21 |