The National Science Foundation (NSF) awarded a $274,438 SBIR Phase I grant to Script Biosciences Inc. under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program. The project, titled "CASPLUS: A Safer, More Efficient, and Targeted Method of Deploying CRISPR In Vivo," aims to develop a platform technology that significantly reduces the potential inaccuracy of current gene editing techniques. The innovation targets the desired gene, increasing the safety and efficacy of...
Biotech Naturale Inc. received a $256,000 Project Grant award from the National Science Foundation Division of Industrial Innovation under the Engineering federal grant program (CFDA 47.041) for the period of August 1, 2021 through July 31, 2022. The grant funds the development of a simple, targeted, and flexible method for transferring value-added genes from wild relatives of crop plants. The Engineering program seeks to improve quality of life and economic strength through fostering innovation...
This Project Grant award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships program) provides $275,000 to Ubiquitx Inc., a New York-based small business, to develop a programmable, modular therapeutic platform for the direct modification of proteins of interest (POIs) using artificial intelligence, protein engineering, and mRNA therapeutics. The goal is to expand the applications of the company's Chimeric Ligands for Induced Proximity (CLIPS)...
This Project Grant award of $968,613 from the National Science Foundation Division of Molecular and Cellular Biosciences supports research into developing a novel CRISPR synthetic biology tool for investigating and reprogramming alkaloid biosynthesis regulation in Catharanthus roseus. The award was made on March 1, 2021 to Northeastern University for work to be completed by December 31, 2024 under the Biological Sciences program (CFDA 47.074). A sub-award of $100,000 was also provided to...
This National Science Foundation Project Grant, funded under the Engineering program (CFDA 47.041), aims to improve the stability and sensitivity of a heat-resistant version of the CRISPR-Cas13 enzyme for accurate and robust detection of disease-causing RNA. The $200,000 award, effective November 1, 2024 through October 31, 2027, supports the University of Connecticut's efforts to engineer the Cas13 enzyme for enhanced thermostability, protease resistance, and target sensitivity. The...
Biochip Labs Inc. received a $256,000 National Science Foundation Project Grant under the Engineering program (CFDA 47.041) for the period of June 1, 2021 through May 31, 2022. The grant funding supports the company's work to develop standardized and reproducible culture and activation methods for endothelial cells in microfluidic devices for drug screening applications. The NSF Engineering program seeks to improve quality of life and economic strength through engineering research and...
The National Science Foundation Division of Industrial Innovation awarded $255,478 under the Engineering (47.041) federal grant program to Crossmhv, L.l.c. (doing business as Nascence) for the project "STTR PHASE I: RAPID-RELEASE CELL CULTURE PLATFORM FOR FLOW CYTOMETRY." The one-year project period runs from January 1, 2022 to December 31, 2022. Under this Project Grant, Nascence will develop a rapid-release cell culture platform to enable high-throughput flow cytometry analysis....
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $305,000 to Cellecho, Inc. supports the development of a microchip-based technology that leverages sound waves and electric fields to enable advanced cell engineering. The goal is to make complex cellular modifications, such as multiplex genome editing, more accessible for a wide range of users from students to experienced researchers. The technology aims to streamline processes...
The National Science Foundation awarded Cytorecovery Inc. a $255,986 Small Business Technology Transfer Phase I Project Grant under the Engineering program (CFDA 47.041) on March 15, 2021. The grant funded the development of on-chip integration of sample preparation and monitoring capabilities with dielectrophoretic cell isolation techniques. The Engineering program seeks to improve quality of life and economic strength by fostering innovation and excellence in engineering research. This award...
The National Science Foundation Division of Industrial Innovation awarded $255,700 to Creative Biotherapeutics LLC through its Engineering program (CFDA 47.041) on January 15, 2021 to fund the project "SBIR PHASE I: STRESS PATHWAY INHIBITION PREVENTS COVID-19 INFECTION (COVID-19)." This Project Grant will support Creative Biotherapeutics' research efforts through December 31, 2021 to develop inhibitors of stress response pathways to prevent COVID-19 infection. The NSF Engineering...