Project Grant 2026176

This federal Project Grant award of $413,298.00 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), will support the development of a novel transmucosal local anesthetic cocktail (T-LAC) formulated into adhesive wafers for the treatment of subacute intraoral pain (IOP). The project, conducted by Trekka Therapeutics, LLC, in partnership with researchers at the University of Minnesota, aims to establish the...

This $2,668,301 Project Grant was awarded by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), under the Drug Use and Addiction Research Programs (CFDA 93.279). The grant funds the development of an implantable, biodegradable drug delivery device for localized, long-duration administration of non-opioid pain medications after surgery. The University of Connecticut will synthesize protein-based film materials conjugated with...

This SBIR Phase I Project Grant, awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program, is developing a novel minimally invasive procedure for deploying an implantable spinal cord stimulation (SCS) lead using a shape memory polymer (SMP). The $304,259 project, which runs from October 1, 2025 to June 30, 2026, aims to create an 8-channel SMP-based paddle lead that can be molded into a compact configuration for minimally...

This Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports the development of PAIN VITALS, an AI-powered wearable physiological sensor system for continuous and objective monitoring of post-surgical pain. The $349,855 award to Aventusoft L.L.C., a minority-owned small disadvantaged business in Boca Raton, FL, will fund the design, development, and clinical testing of this innovative...

This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $350,027 to Asko Therapeutics, Inc. to develop novel injectable implants for the long-term local controlled release of therapeutic monoclonal antibodies. The goal is to create injectable PLGA (poly(lactic-co-glycolic acid)) implants that can stably encapsulate and continuously release therapeutic monoclonal antibodies for...

This Cooperative Agreement award of $1,278,689 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to develop an automated Neonatal Pain Monitoring System (NPMS) and pain management protocol to objectively measure and minimize postoperative pain in newborns. The project has two key objectives: 1) Develop and validate AI-driven neonatal pain biomarker signatures and an automated NPMS to continuously...

This federal Project Grant award of $431,750.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to explore the role of the chemokine CCL12 in alleviating postoperative pain. The research aims to test whether neutralizing CCL12 is effective and safe for reducing pain after surgery, and to investigate the mechanisms by which CCL12 induces nociception. The project...

Teliatry Inc. received a $768,138 project grant award from the National Institutes of Health's National Institute of Biomedical Imaging and Bioengineering to develop a minimally invasive, single incision, rechargeable spinal cord stimulation system for chronic pain management. The grant was awarded under the Discovery and Applied Research for Technological Innovations to Improve Human Health program. Through this award, Teliatry will engineer the world's smallest (0.75cc), most cost-effective...

This federal Project Grant award from the National Institutes of Health (CFDA 93.279 - Drug Abuse and Addiction Research Programs) provides $1,105,489 to The Leland Stanford Junior University (Stanford University) to fund research aimed at reducing the risk of persistent postoperative opioid use and opioid use disorder among older adults undergoing inpatient surgery. The key products and services to be delivered under this 2-year grant include: Augmenting an existing dataset that links...

This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), provides $3,473,616 to the University of Connecticut to develop a novel implantable neuromodulation system called "SmartStim" to treat chronic pain. The goal is to create a combined device and drug treatment that can selectively block sensitized nociceptive (pain-sensing) nerve fibers, especially C-fibers, to reverse the underlying neural...