Project Grant 20253361044937
- The U.S. Department of Agriculture (USDA) awarded a $300,000 grant under the Agriculture and Food Research Initiative (AFRI) program to Oklahoma State University (OSU) to develop a novel single-cycle vaccine against bovine respiratory syncytial virus (BRSV). The project aims to pioneer the development of two single-cycle BRSV vaccine prototypes: an 'MNull' vaccine that lacks the essential matrix protein, and a 'PRef' vaccine with a modified fusion protein. OSU will evaluate the immunogenicity...
- The Department of Agriculture's National Institute of Food and Agriculture awarded Kansas State University $650,000 under the Agriculture and Food Research Initiative competitive grants program to develop improved vaccines for bovine respiratory disease complex. With funding through May 2026, the university aims to generate new knowledge needed to design vaccines capable of protecting calves against multiple strains of Bovine parainfluenza virus 3 and Bovine viral diarrhea virus. Researchers...
- Long Island University received a three-year, $627,000 Project Grant award from the United States Department of Agriculture National Institute of Food and Agriculture under the Agriculture and Food Research Initiative competitive grants program. The grant will fund research to develop an improved vaccine for bovine respiratory disease (BRD) in cattle. BRD costs the U.S. beef industry over $3 billion annually. Current commercial vaccines have limited effectiveness. The university will generate...
- The U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) awarded a $599,455 Project Grant under the Small Business Innovation Research (SBIR) Program (CFDA 10.212) to VST LLC (DBA Medgene Labs) located in Brookings, SD. The purpose of this 2-year grant is to develop the first U.S.-based vaccine against the invasive Asian Longhorned Tick, which poses a major threat to animal health and productivity in cattle and other livestock. The vaccine will be...
- The U.S. Department of Agriculture's (USDA) National Institute of Food and Agriculture (NIFA) awarded a $175,000 Small Business Innovation Research (SBIR) Phase I grant (CFDA 10.212) to Seismi Inc. to develop the Seismi Health Monitoring Device. This battery-free, wirelessly powered biosensor is designed to be integrated into cattle ear tags to continuously monitor vital signs like heart and respiratory rates. The goal is to provide an early detection system for bovine respiratory disease...
- This $300,000 federal Project Grant award from the USDA National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (CFDA 10.310) will support the development and testing of a novel vaccine against Mycoplasma ovipneumoniae, a bacterium that infects sheep and causes respiratory disease. The project aims to design a vaccine that incorporates biofilm components to induce a strong immune response in the respiratory tract and prevent or clear M....
- This $649,896 federal Project Grant awarded by the U.S. Department of Agriculture's (USDA) National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program supports the development and testing of an mRNA vaccine cocktail against influenza A viruses (IAV) in livestock. The project aims to create a universal influenza vaccine that can provide broad protection against diverse IAV strains, including highly pathogenic avian influenza (HPAI) H5N1...
- The U.S. Department of Agriculture (USDA) awarded a $650,000 project grant to Oklahoma State University (OSU) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310). The grant aims to identify cellular and viral genes that induce reactivation of Bovine Herpesvirus 1 (BoHV-1) from latency in cattle. Understanding the mechanisms of BoHV-1 reactivation will allow the development of improved vaccine strategies to reduce the spread of the virus and incidence of Bovine...
- The U.S. Department of Agriculture's (USDA) National Institute of Food and Agriculture (NIFA) awarded a $800,000 Project Grant under the Agriculture and Food Research Initiative (AFRI) program to Washington State University (WSU). The grant aims to develop a vaccine against anaplasmosis, a prevalent tick-borne infection in cattle that causes significant morbidity and an estimated $300 million in annual economic losses in the U.S. The project will test the protective capacity of outer membrane...
- The U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) awarded a $800,000 Project Grant under the Agriculture and Food Research Initiative (AFRI) program to the University of Pittsburgh. The funding will support the development of new diagnostic tests to monitor Influenza D virus (IDV) in cattle and other livestock, as well as the creation of an innovative nasal spray vaccine to protect cattle from IDV and prevent the disease from spreading. This research aims...
This $174,699 project grant was awarded by the U.S. Department of Agriculture's (USDA) National Institute of Food and Agriculture (NIFA) under the Small Business Innovation Research (SBIR) Program. The grant was awarded to Thyreos Inc., a biotechnology and vaccine development company, to develop an integrated vaccine that provides broad protection against the three major viral contributors to Bovine Respiratory Disease (BRD) in cattle. Specifically, the project aims to engineer a single vaccine that expresses protective antigens from Bovine Herpesvirus Type 1, Bovine Respiratory Syncytial Virus, and Bovine Parainfluenza Virus. This multiplexed vaccine is designed to offer improved safety and cost-effectiveness compared to current BRD vaccines, with the goal of enhancing animal health, reducing antibiotic use, and mitigating the significant financial impact of BRD on the cattle industry. The project period runs from August 15, 2025 to April 14, 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $174.7k | 8/4/25 |