** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** THE USE OF PESTICIDES, THOUGH VERY IMPORTANT FOR HIGHER AGRICULTURAL YIELDS, RELEASES HAZARDOUS CHEMICALS INTO THE ENVIRONMENT. EFFECTIVE, TIMELY DETECTION OF THESE PESTICIDES IS CRUCIAL TO PREVENT WIDESPREAD DAMAGE. CURRENT DETECTION METHODS, RELYING ON LABORATORY-ORIENTED CHROMATOGRAPHY COUPLED WITH MASS SPECTROMETRY, ARE PRECISE BUT LACK FIELD APPLICABILITY DUE TO THEIR TIME-CONSUMING PROCEDURES, BULKY INSTRUMENTS, AND THE REQUIREMENT OF SKILLED PERSONNEL. THE EXISTING FIELD-DEPLOYABLE ENZYMATIC OR NON-ENZYMATIC METHODS SUFFER FROM POOR SELECTIVITY AND SPECIFICITY, WHICH MAKE THEM NOT IDEAL FOR IN-FIELD PESTICIDES MONITORING EITHER. THERE IS AN URGENT NEED FOR INNOVATIVE, FIELD-DEPLOYABLE PESTICIDE DETECTION TECHNOLOGIES TO ENSURE ENVIRONMENTAL AND PUBLIC HEALTH. THIS PROPOSAL AIMS AT DEVELOPING A SENSOR USING MOLECULARLY IMPRINTED JANUS GOLD NANOPARTICLES FOR QUICK, SENSITIVE, AND SIMPLE IN-FIELD PESTICIDE DETECTION. THIS TECHNOLOGY LEVERAGES AN INNOVATIVE MIP PROCESS ON JANUS GOLD NANOPARTICLES AND A UNIQUE SIGNAL AMPLIFICATION STRATEGY FOR ENHANCED SENSITIVITY AND SELECTIVITY. HIGH ACCURACY AND REPRODUCIBILITY WILL BE ENSURED BY COLLECTING THE SIGNAL OVER THE WHOLE SENSING SPOT. THE SENSOR WILL FINALLY BE VALIDATED AT UCONN FARM SITE UNDER AN AGRICULTURE RELEVANT SCENARIO.