This $800,000 Project Grant awarded by the U.S. Department of Agriculture's (USDA) National Institute of Food and Agriculture (AFRI program, CFDA 10.310) supports the development of critical solutions to address the increasing risk of Influenza D virus (IDV) in cattle and livestock. The research team from the University of Pittsburgh, in collaboration with South Dakota State University, is focused on two key objectives: Developing new diagnostic tests to effectively monitor the spread of IDV...
Long Island University received a three-year, $627,000 Project Grant award from the United States Department of Agriculture National Institute of Food and Agriculture under the Agriculture and Food Research Initiative competitive grants program. The grant will fund research to develop an improved vaccine for bovine respiratory disease (BRD) in cattle. BRD costs the U.S. beef industry over $3 billion annually. Current commercial vaccines have limited effectiveness. The university will generate...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), is focused on understanding the molecular basis for differences in vaccine efficacy between various sub-strains of the Bacillus Calmette-Guérin (BCG) tuberculosis vaccine. The total funding amount is $749,192, awarded on November 22, 2024, with a completion date of October 31, 2029. The key objectives of this research project...
This $300,000 federal Project Grant award from the USDA National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (CFDA 10.310) will support the development and testing of a novel vaccine against Mycoplasma ovipneumoniae, a bacterium that infects sheep and causes respiratory disease. The project aims to design a vaccine that incorporates biofilm components to induce a strong immune response in the respiratory tract and prevent or clear M....
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $820,246 to the Albert Einstein College of Medicine to identify and characterize the specific proteins secreted by the ESX5 transport system of the tuberculosis (TB) bacterium. The research aims to determine the role of these secreted proteins in causing TB disease and the immunological basis for why an ESX5 mutant...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $817,405.00 to Colorado State University and its subrecipient, the University of Tennessee Health Science Center, to develop new drug regimens for treating tuberculosis (TB), including both drug-sensitive and multidrug-resistant strains. The key objectives are to: 1) manufacture and characterize inhalable dry...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will provide $1,162,224 to the University of Pittsburgh to optimize and evaluate an oral Bacille Calmette-Guérin (BCG) vaccine regimen against tuberculosis (TB). The key objectives are to: 1) optimize an oral BCG vaccination approach, 2) compare the efficacy of oral BCG to the current standard intradermal and intravenous BCG...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) provides $905,998 to the Texas Biomedical Research Institute to evaluate the safety, immunogenicity, and efficacy of an attenuated Mycobacterium tuberculosis (MTB) vaccine in the setting of HIV co-infection. The research aims to understand whether this novel attenuated MTB vaccine candidate can induce protective immune...
This Project Grant award from the USDA National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) (CFDA 10.310) supports research to study the effects of Bovine Viral Diarrhea Virus (BVDV) on the thymus and T-cell receptors in cattle. The $300,000 award to Oklahoma State University aims to better understand how BVDV damages the thymus, a key organ for T-cell development, and impacts T-cell receptor diversity, which is crucial for an effective...
This $300,000 Project Grant awarded by the USDA National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program supports research at Texas Tech University to investigate the impact of Bovine Leukemia Virus (BLV) on dairy cow immune systems. The project will employ advanced single-cell RNA sequencing techniques to examine changes in blood cell function at the molecular level in BLV-infected cattle. The goal is to uncover specific weaknesses in...