Project Grant 20246701242409
- Federal Grant Award Summary Texas A&M AgriLife Research received a $779,000 project grant from the U.S. Department of Agriculture's National Institute of Food and Agriculture under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310), awarded January 15, 2026, with completion targeted for January 14, 2029. The project addresses bovine respiratory disease (BRD), a significant health and economic challenge affecting the U.S. beef industry. The research will investigate the...
- Federal Grant Award Summary Texas A&M Agrilife Research received a $300,000 Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310), effective January 15, 2026 through January 14, 2028. The award supports development of BRDSeq, a molecular diagnostic tool designed to identify and characterize disease-causing bacteria and viruses associated with bovine respiratory...
- The Department of Agriculture's National Institute of Food and Agriculture awarded a $650,000 Project Grant to the Agricultural Research Service to fund research under the Agriculture and Food Research Initiative competitive grants program. The grant will support research from June 2023 to May 2027 focusing on the liver and blood microbiome changes and their relationship to ruminal acidosis in dairy cattle. The research aims to investigate membership and longitudinal shifts in the liver and...
- The Department of Agriculture's National Institute of Food and Agriculture awarded $650,000 under the Agriculture and Food Research Initiative competitive grants program to identify genetic and biological markers correlated with the development of liver abscesses in feedlot cattle. With a project period from June 2023 through May 2028, this Project Grant will support research at the Agricultural Research Service Plains Area in Fort Collins, Colorado to address the prevalent and costly issue of...
- The U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) awarded a $800,000 Project Grant under the Agriculture and Food Research Initiative (AFRI) program to the University of Pittsburgh. The funding will support the development of new diagnostic tests to monitor Influenza D virus (IDV) in cattle and other livestock, as well as the creation of an innovative nasal spray vaccine to protect cattle from IDV and prevent the disease from spreading. This research aims...
- This federal Project Grant award of $237,204.00 from the USDA's National Institute of Food and Agriculture (NIFA), under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310), will fund research into using gut microbiome modulation as an alternative approach to control Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) in swine. The key objectives of this 18-month project, led by the Regents of the University of Minnesota, are to investigate the effects of microbiome...
- This federal Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (CFDA 10.212 - Small Business Innovation Research (SBIR) Program / Small Business Technology Transfer (STTR) Program) provides $175,000 to Seia Bio Inc. to develop a proprietary coating technology that protects beneficial probiotic microbes, such as Faecalibacterium, from environmental stressors. This will enable the expanded use of these microbes as alternatives to antibiotics...
- The U.S. Department of Agriculture's National Institute of Food and Agriculture awarded a $169,028 Project Grant to Hoofprint Biome, Inc. under the Small Business Innovation Research (SBIR) Program (CFDA 10.212). The funding supports the development of a scalable probiotic solution to reduce methane emissions from cattle. Hoofprint Biome is innovating a library of natural, bioactive peptides that inhibit methane production by microbes in the cattle rumen. The goal is to engineer the secretion of...
- This $300,000 project grant from the United States Department of Agriculture National Institute of Food and Agriculture will fund research at Prairie View A&M University to study the relationship between bacterial infection, inflammatory response, and proteolysis of casein in milk. Specifically, the university researchers will measure immune cell profiles and expression of inflammatory cytokines in milk leukocytes using flow cytometry and ELISA techniques. They will also conduct an...
- This $799,462 project grant was awarded on March 15, 2025 by the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310). The goal is to create predictive models for how the highly pathogenic avian influenza (HPAI) outbreak in U.S. dairy cattle could continue spreading across the country based on cattle shipment data and disease transmission factors. The key objectives are to: 1) collect...
** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** BOVINE RESPIRATORY DISEASE (BRD) IS THE MOST DEVASTATING DISEASE AFFECTING U.S. CATTLE PRODUCERS. ALTHOUGH MANY ETIOLOGICAL AGENTS HAVE BEEN IMPLICATED IN BRD, A BACTERIAL INFECTION WITH THE OPPORTUNISTIC PATHOGEN MANNHEIMIA HAEMOLYTICA IS MOST OFTEN OBSERVED. ALTHOUGH MUCH RESEARCH HAS FOCUSED ON BRD, MORBIDITY AND MORTALITY HAVE NOT DECLINED IN THE PAST 45 YEARS, AND ANTIMICROBIAL RESISTANCE, ESPECIALLY IN M. HAEMOLYTICA, HAS BEEN OBSERVED. AS A RESULT, THERE IS A PRESSING NEED FOR NOVEL PREVENTATIVES. AS IT IS KNOWN THAT THE RESPIRATORY MICROBIOTA OF CALVES WITH BRD DIFFERS FROM THAT OF HEALTHY CALVES, IT IS POSSIBLE THAT PROBIOTICS FROM THE BOVINE RESPIRATORY MICROBIOTA MAY BE THE ANSWER. OUR PRELIMINARY DATA INDICATE THAT COMMENSAL CORYNEBACTERIUM FROM THE BOVINE RESPIRATORY TRACT CAN INHIBIT M. HAEMOLYTICA GROWTH IN VITRO, POTENTIALLY DUE TO THEIR ABILITY TO PRODUCE SECONDARY METABOLITES. HOWEVER, THE METABOLITES, THE MANNER OF INHIBITION, AND OTHER PROBIOTIC PROPERTIES POSSESSED BY THESE ISOLATES ARE UNKNOWN. AS A RESULT, THE OVERALL OBJECTIVE OF THIS PROJECT IS TO FURTHER CHARACTERIZE THE PROBIOTIC CAPABILITIES OF OUR COMMENSAL CORYNEBACTERIUM ISOLATES, PROVIDING VALUABLE DATA REGARDING THE ROLE WITHIN THE BOVINE RESPIRATORY MICROBIOTA, AS WELL AS THEIR POTENTIAL TO SERVE AS EFFECTIVE PROBIOTICS FOR BRD PREVENTION. THE DEVELOPMENT OF A PROBIOTIC FOR BRD PREVENTION WOULD BE HIGHLY VALUABLE AS IT WILL IMPROVE CATTLE HEALTH WHILE REDUCING ANTIMICROBIAL USAGE, INCREASING PRODUCER PROFITABILITY, AND ENSURING A SUSTAINABLE AND SAFE FOOD SUPPLY.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 3/18/26 | ||
| Not listed | $225.0k | 5/10/24 |