Project Grant 20243882142108
- This $298,879 project grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the 1890 Institution Capacity Building Grants (CFDA 10.216) program will enable Fort Valley State University (FVSU) to achieve two main objectives: Build the university's capacity to develop and teach an undergraduate course on CRISPR genome editing technology, in collaboration with the University of Hawaii. This will help prepare future science professionals to...
- This $1,211,545 Project Grant award from the National Science Foundation (CFDA 47.074 - Biological Sciences) will support the development of advanced Prime Editing (PE) systems in rice, tomato, and poplar plants. Prime Editing is a novel and highly versatile CRISPR-based gene editing technology that enables precise genome modifications. The key objectives of this 3-year project are to optimize Prime Editor proteins to increase their activity and editing efficiency, improve pegRNA structure and...
- This Project Grant award, valued at $299,932 and provided by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074), aims to improve the efficiency of a bacterial DNA editing tool, CRISPR/Cas, for use in two model plant species - tobacco and Arabidopsis. The research will leverage the CRISPR/Cas system to enable a broader array of DNA sequence changes in plants, which could lead to the development of superior crop varieties that are more resilient to extreme weather...
- This $725,512 project grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) aims to develop highly efficient and robust prime editing systems in rice, tomato, and poplar plants. Prime editing is an advanced CRISPR/Cas gene editing technology that enables precise gene modifications, offering significant advantages over conventional CRISPR approaches. The project will optimize prime editor proteins, improve prime editor guide RNA structures and...
- This Project Grant awarded by the United States Department of Agriculture's National Institute of Food and Agriculture under the Biotechnology Risk Assessment Research Grants Program (CFDA 10.219) provides $649,753 to the University of Maryland, College Park to conduct research on the unintended effects of multiplexed genome editing using cytosine base editors (CBEs) in rice. The key objectives are to: 1) develop improved CBEs derived from CRISPR-Cas9 and CRISPR-Cas12a for high-efficiency...
- This $300,000 federal Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the 1890 Institution Capacity Building Grants (CFDA 10.216) program aims to develop a CRISPR-based research and training platform at Alabama A&M University (AAMU) to enhance biofuel production using the oleaginous yeast Yarrowia lipolytica. The project seeks to leverage CRISPR gene editing to identify and modify key genes involved in lipid...
- This $322,020 Project Grant award from the National Science Foundation's (NSF) Division of Integrative Organismal Systems will support collaborative research at the University of California, Davis (UC Davis) to develop improved methods for CRISPR/Cas9-based gene editing in maize. The key objectives are to generate maize lines expressing high levels of Cas9 nuclease and to engineer and optimize viral vectors to efficiently deliver guide RNAs for both somatic and heritable gene editing. This...
- The National Science Foundation (NSF) awarded a $800,000 Project Grant under its Biological Sciences program (CFDA 47.074) to The Regents of the University of California, doing business as University of California, Berkeley. The grant funding will support collaborative research to discover and characterize compact CRISPR gene editing systems that can be encoded in plant viruses. This will enable more efficient and widespread deployment of genome editing capabilities across a variety of crop...
- This $225,000 federal Project Grant from the USDA's Agriculture and Food Research Initiative (CFDA 10.310) aims to improve the agronomic traits of pennycress to enhance its potential as an emerging cash cover crop. The project will leverage computational protein simulation and CRISPR-Cas gene editing technologies to identify and introduce beneficial genetic variants that result in earlier flowering, larger seed sizes, and improved root architecture in pennycress. The goal is to accelerate the...
- This Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the 1890 Institution Capacity Building Grants (CFDA 10.216) program provides $491,739.82 to Florida A&M University (FAMU) to conduct research aimed at developing non-leathery, crispy muscadine grapes. The 3-year project from January 1, 2026 to December 31, 2028 will take an integrated omics approach to identify and characterize the genes, transcripts, proteins, and...
This Project Grant award of $485,312 from the USDA National Institute of Food and Agriculture under the 1890 Institution Capacity Building Grants Program (CFDA 10.216) supports research at Fort Valley State University (FVSU) to establish an efficient CRISPR/Cas9 gene editing system for improving Rhizoma peanut (RP), a high-quality warm-season forage legume. The key objectives are to investigate CRISPR guide RNA design, construction, and delivery methods to overcome challenges in editing the multiple alleles of this polyploid crop, which has breeding impediments like poor seed setting and sterility. By targeting the RP phytoene desaturase (PDS) gene as a visual marker, the project aims to validate an effective reagent combination for RNP-mediated RP editing. This research aligns with USDA-NIFA's strategic goal of ensuring an equitable, resilient, and prosperous agricultural system. The award period is from April 1, 2024 to March 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $485.3k | 3/28/24 |