Project Grant 20243353041954
- The University of Nebraska was awarded a $225,000 Project Grant from the U.S. Department of Agriculture's (USDA) Agriculture and Food Research Initiative (AFRI) program to conduct research aimed at improving the quality and development of in vitro produced (IVP) embryos for beef and dairy cattle. The goal is to understand how oxidative stress during oocyte culture impacts gene regulation and developmental competence of IVP embryos. The researchers will perform culture of oocytes under...
- This Project Grant award from the U.S. Department of Agriculture's (USDA) National Institute of Food and Agriculture (NIFA) Small Business Innovation Research (SBIR) Program (CFDA 10.212) provides $175,000 to Emgenisys Inc. to develop a non-invasive, real-time tool that uses artificial intelligence and machine learning to predict the sex of bovine embryos. The technology, which involves recording a 30-second video of an embryo on a smartphone, aims to enable beef and dairy producers to make more...
- Virginia Polytechnic Institute & State University (Virginia Tech) was awarded a $120,000 Project Grant from the United States Department of Agriculture's National Institute of Food and Agriculture under the Agriculture and Food Research Initiative competitive grants program. The two-year grant aims to combat high rates of pregnancy failure for cattle embryos produced through in vitro fertilization techniques. Virginia Tech researchers will modify embryo culture media by including...
- The Department of Agriculture's National Institute of Food and Agriculture awarded a $120,000 Project Grant under the Agriculture and Food Research Initiative competitive grants program to Virginia Polytechnic Institute & State University from July 2021 through June 2023. The grant funds research to investigate embryonic losses occurring during blastocyst hatching and embryo elongation in cattle, which can significantly impact the cattle industry. The principal investigator will...
- Virginia Polytechnic Institute and State University (Virginia Tech) was awarded a $180,000 project grant from the United States Department of Agriculture National Institute of Food and Agriculture to study early embryonic development in cattle through the Agriculture and Food Research Initiative competitive grants program. The goal of the three-year project beginning June 1, 2023 is to prevent pregnancy loss in cattle and humans, which accounts for over half of pregnancies in the first month...
- This Project Grant from the United States Department of Agriculture's National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) program provides $500,000 to Texas A&M Agrilife Research to study neuroendocrine control of reproduction in cattle breeds. The goal is to determine if distinct differences in reproductive function between Bos indicus and Bos taurus cattle can be attributed to differences in hypothalamic and pituitary function. The awardee will...
- The federal Project Grant award of $650,000.00 from the USDA National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program supports research by Colorado State University to improve fertility and reproductive efficiency in the beef and dairy cattle industries. The project aims to activate the Nrf2 signaling pathway in bovine preimplantation embryos to mitigate oxidative stress and enhance embryo survival under suboptimal conditions,...
- This $650,000 Agriculture and Food Research Initiative (AFRI) Project Grant, awarded by the USDA National Institute of Food and Agriculture (CFDA 10.310), aims to improve the reproductive success of high-producing dairy cows. The research project has two main objectives: 1) understanding the nutritional needs of dairy cow embryos, particularly differences between lactating cows and younger heifers, in order to identify ways to better support embryo development; and 2) examining how oxygen and...
- This $500,000 project grant from the Department of Agriculture's National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) program will develop new selection tools to improve male fertility in beef cattle. Awarded to Kansas State University on May 1, 2021 for a five-year period concluding on April 30, 2026, the grant will result in prototype tools utilizing conception data, semen quality metrics, and breeding soundness examination results on beef bulls....
- This $300,000 Project Grant from the USDA National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) program, awarded to Utah State University (USU) on July 1, 2024, aims to improve the efficiency of cattle cloning by studying the impact of increased polyadenylation (adding stabilizing tails to genetic messages) on egg quality and embryo development. The research hypothesis is that enhancing polyadenylation will lead to higher quality eggs, thereby...
EFFICIENT CATTLE PRODUCTION SUPPORTS THE LIVESTOCK INDUSTRY, 10S OF THOUSANDS OF FARMERS, AND PROVIDES MILLIONS OF PEOPLE WITH IMPORTANT NUTRITION. ASSISTED REPRODUCTIVE TECHNOLOGIES(ART) HAVE BEEN DEVELOPED TO IMPROVE CATTLE PRODUCTION. BOVINE ART INCLUDES ARTIFICIAL INSEMINATION (AI), EMBRYO TRANSFER (ET), AND IN VITRO FERTILIZATION (IVF). THE MOST ADVANCED TECHNOLOGY IS IVF, YET IT HAS THE LOWEST EMBRYO PRODUCTION RATE BECAUSE OF TECHNICAL AND PROCESS PROBLEMS. POOR EFFICIENCY LEADS TO DECREASED FARMERSUSTAINABILITY AND THE PRODUCTION OF POOR-QUALITY COWS THAT MAY PRODUCE LESS MILK OR HIGH-QUALITY BEEF. IMPROVING THE PRODUCTION OF GENETICALLY SUPERIOR COWS WITH MULTIPLE OFFSPRING WILL BENEFIT THE FARMER, CONSUMER, AND ENVIRONMENT.REPROHEALTH SOLVES THESE PROBLEMS WITH OUR NOVEL BOVINE INTRA VAGINAL EMBRYO CULTURE (IVC) DEVICE. EMBRYOS AND GROWN IN A SMALL DEVICE, ABOUT THE SIZE OF A THUMB, IN THE COW'S VAGINA. THE DEVICE IS TAKEN OUT OF THE COW'S VAGINA AFTER 7 DAYS AND THE EMBRYOS ARE TRANSFERRED TO RECIPIENT COWS TO ESTABLISH A PREGNANCY. WE WILL GENERATE LARGE AMOUNTS OF DATA CHARACTERIZING THE QUALITY OF THE EMBRYOS AS COMPARED TO CONVENTIONAL IVF AND WE WILL PUBLISH THIS IN SCIENTIFIC JOURNALS. WE ARE TARGETING FARMERS THAT ARE CURRENTLY DOING IVF TO MAINTAIN THEIR HERDS AND WE ARE WORKING WITH SEVERAL KEY INDUSTRY LEADERS TO ADVANCE OUR TECHNOLOGY. WE SEE MANY BENEFITS OF THIS TECHNOLOGY OVER ARTIFICIAL INSEMINATION AND PLAN TO SHOW ITS SUPERIORITY IN THE FUTURE.ULTIMATELY WE ARE DEVELOPING A COMPLETELY NEW FORM OF CATTLE ASSISTED REPRODUCTIVE TECHNOLOGY. THIS TECHNOLOGY WILL 'BRING THE IVF LAB TOTHE FARM.' THIS ADVANCED METHOD OF CONCEPTION WILL LOWER THE COST OF PRODUCTION BY IMPROVING THE EFFICIENCY OF EMBRYO PRODUCTION AND THUS PREGNANCY. BY GETTING MULTIPLE OFFSPRING OF THE COWS WITH THE BEST GENETIC TRAITS, FEWER COWS WILL BE NEEDED TO MEET THE CUSTOMER DEMAND. WE FEEL STRONGLY THAT WE HAVE A RESPONSIBILITY TO HELP WORLDWIDE FOOD INSECURITY WITH OUR TECHNOLOGY. A TECHNOLOGY THAT IS EASY TO USE AND INCREASES CATTLE PRODUCTION WOULD GIVE PROTEIN AND MILK TO THE MILLIONS OF PEOPLE WHO SUFFER FROM FOOD INSECURITY.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | ($11k) | 7/17/25 | ||
| Not listed | $175.0k | 3/15/24 |