Project Grant 20236701140341

Award Date 6/1/23
Completion Date 5/31/26
Dollars Obligated $180K
Federal Grant Program
10.310
Assistance Type
Project Grant
Place of Performance
Blacksburg, VA 24061, USA
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Virginia Polytechnic Institute and State University (Virginia Tech) was awarded a $180,000 project grant from the United States Department of Agriculture National Institute of Food and Agriculture to study early embryonic development in cattle through the Agriculture and Food Research Initiative competitive grants program.

The goal of the three-year project beginning June 1, 2023 is to prevent pregnancy loss in cattle and humans, which accounts for over half of pregnancies in the first month of development. Virginia Tech researchers will use in vitro production of embryos to study extraembryonic membrane formation and function, and supplement embryos with interleukin-6 to improve quality. Researchers will also inhibit the interleukin-6 receptor to determine if this signaling is necessary for embryonic survival. The project aims to describe the necessity of interleukin-6 signaling in extraembryonic membrane formation and function to help improve cattle pregnancy rates and reduce loss, with potential applications for human embryonic development as well.

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