Project Grant 20236701438990

Award Date 5/1/23
Completion Date 4/30/28
Dollars Obligated $681K
Federal Grant Program
10.310
Assistance Type
Project Grant
Place of Performance
Bozeman, MT 59717, USA
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Montana State University will receive $681,422 under a five-year Project Grant from the United States Department of Agriculture National Institute of Food and Agriculture to research honey bee antiviral defense mechanisms and develop biologically-based treatments to combat viral infections. The research directly addresses goals of the USDA's Agriculture and Food Research Initiative (AFRI) competitive grants program (CFDA #10.310) to understand pathogen impacts on pollinator health and mitigate pollinator losses.

Specifically, Montana State University researchers will study the virus-limiting efficacy of immune stimulatory compounds like thyme oil/thymol or poly(I:C) in honey bees experimentally infected with Deformed Wing Virus, Israeli Acute Paralysis Virus, and Sacbrood Virus. They will also examine potential unintended consequences on bee health, gene expression, and physiology. The laboratory-based studies aim to determine the most efficacious treatments prior to future field research involving hundreds of honey bee colonies. Results of this work could further the development of biologically-based immunostimulatory compounds to reduce honey bee virus levels and mitigate annual colony losses critical to U.S. agriculture.

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