Project Grant 20233882139922
- Federal Grant Award Summary The Boyce Thompson Institute for Plant Research Inc. received a $649,672 Project Grant award from the USDA's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310), effective March 1, 2026, through February 28, 2029. The project will deliver fundamental research aimed at identifying the molecular mechanisms underlying blossom end rot (BER) resistance in tomato fruit with starch-deficient...
- Federal Project Grant Award Summary Award Details: Funding Agency: U.S. Department of Agriculture, National Institute of Food and Agriculture (NIFA) Federal Grant Program: Agriculture and Food Research Initiative (AFRI) – CFDA 10.310 Awardee: Boyce Thompson Institute For Plant Research Inc. Award Amount: $730,000 Award Period: April 1, 2026 – March 31, 2030 Performance Location: Ithaca, New York Products and Services Delivered: The Boyce Thompson Institute will implement a comprehensive...
- Federal Project Grant Award Summary The University of Maryland, College Park received a $649,999 Project Grant award from the United States Department of Agriculture National Institute of Food and Agriculture (USDA-NIFA) under the Biotechnology Risk Assessment Research Grants Program (BRAG, CFDA 10.219), effective September 15, 2025, through September 14, 2029. The award supports research designed to evaluate the efficacy and specificity of multiplex genome editing as a tool for engineering...
- The National Science Foundation awarded a $307,400 Project Grant under its Biological Sciences program (CFDA 47.074) to the University of Missouri System to develop epigenetic editing tools for improving crop plants. The project aims to expand the capabilities of genome editing by enabling targeted changes in gene expression, rather than just DNA sequence, to generate novel traits in important crops like rice and tomato. Key objectives include adapting the epigenetic editing approach...
- This three-year National Science Foundation Project Grant of $626,850 supports research to develop a holistic understanding of plant cuticle assembly through synthetic biology approaches. Funded under the Biological Sciences program (CFDA 47.074), the grantee—the University of Nebraska—will engineer yeast and plant root systems lacking natural cuticles to model cuticle metabolism pathways. Researchers will refactor transcriptional networks and metabolic processes to produce synthetic cuticle...
- This $725,512 project grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) aims to develop highly efficient and robust prime editing systems in rice, tomato, and poplar plants. Prime editing is an advanced CRISPR/Cas gene editing technology that enables precise gene modifications, offering significant advantages over conventional CRISPR approaches. The project will optimize prime editor proteins, improve prime editor guide RNA structures and...
- This $1,211,545 Project Grant award from the National Science Foundation (CFDA 47.074 - Biological Sciences) will support the development of advanced Prime Editing (PE) systems in rice, tomato, and poplar plants. Prime Editing is a novel and highly versatile CRISPR-based gene editing technology that enables precise genome modifications. The key objectives of this 3-year project are to optimize Prime Editor proteins to increase their activity and editing efficiency, improve pegRNA structure and...
- Federal Grant Award Summary The University of Georgia Research Foundation, Inc. received a $650,000 project grant from the Institute of Food Production and Sustainability under the Agriculture and Food Research Initiative (AFRI) (CFDA 10.310) awarded on February 15, 2026, with completion expected by February 14, 2029. This research initiative addresses blossom-end rot (BER), a significant disorder affecting tomatoes and numerous other vegetables that causes crop losses up to 50% in severe cases....
- The National Science Foundation's Biological Sciences program awarded a $1,200,000 project grant to the University of California, Los Angeles (UCLA) Office of Research Administration to discover and characterize small CRISPR genome editing systems for virus-based delivery into plants. This 3-year project aims to develop new tools to enhance plant breeding and create crops with higher yields, drought resistance, and pest/temperature tolerance. The work includes screening metagenomic data to...
- This $836,100 federal Project Grant award from the National Science Foundation's Integrative Activities program (CFDA 47.083) aims to enhance understanding of the genetic mechanisms underlying the bacterial wilt disease that affects cucurbit crops like cucumbers and melons. The key objectives are to screen and characterize disease resistance traits in diverse cucumber and melon populations, and leverage this knowledge to develop sustainable management strategies for this critical agricultural...
** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** CUTICLE AND SUBERIN ARE PRODUCED AND CHANGED IN HIGHER PLANTS DURING NORMAL DEVELOPMENT AND IN RESPONSE TO STRESSES, INCLUDING WATER LOSS, WOUNDING, AND PATHOGEN INFECTIONS, ETC. DESPITE THEIR UBIQUITOUS PRESENCES IN DIFFERENT PLANT SPECIES, THE REGULATION OF THE CUTICLE AND SUBERIN BIOSYNTHESIS AND DEPOSITION TO THE PLANT SURFACE AS WELL AS THEIR FUNCTIONAL MECHANISMS IN PLANT DEFENSE ARE LARGELY UNKNOW. TOMATO PLANTS ARE IMPORTANT CROPS IN THE U.S.A AND WORLD-WIDE. MORE THAN 30% OF TOMATO YIELDS COULD BE LOST DURING THE PATHOGEN INFECTIONS AND POSTHARVEST STORAGE. THE DEFECTS OF CUTICLE IN TOMATO FRUITS COULD LEAD TO THE ENHANCED WATER LOSS AND REDUCED TOLERANCE TO BIOTIC AND ABIOTIC STRESSES IN BOTH GROWING SEASON, HARVEST, AND POST-HARVEST STORAGE STAGES. OUR SPECIFIC OBJECTIVES ARE: 1) TO EXPLORE CRISPR GENOME EDITING SYSTEM FOR TOMATO PRODUCTION WITH THE MODIFIED CUTICLE FORMATION AND STRUCTURES; 2) TO SYSTEMICALLY EXAMINE THE ROLES OF THE TARGETED GENES IN CUTICLE FORMATION FORTHEIR RELATED FUNCTIONS IN BIOTIC AND ABIOTIC STRESSES IN TOMATO PLANTS; 3) TO TRAIN 1890 FACULTY AND UNDER-PRIVILEGED STUDENTS IN THE APPLICATION OF THE BIOCHEMICAL, MOLECULAR, AND CELLULAR BIOLOGY AND GENOME EDITING TECHNOLOGY FOR THE ACADEMIC AND RESEARCH ENHANCEMENT. THE GOAL OF THIS PROJECT ALIGNS WELL WITH THE NIFA CBG PROGRAM IN THAT IT ADVANCES OUR KNOWLEDGE ON SUSTAINABLE AGRICULTURE AS WELL AS THE NEXT GENERATION AGRICULTURE WORK FORCE TRAINING BY TWO-INSTITUTE COLLABORATION.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $490.0k | 4/21/23 |