Project Grant 20207041032914

The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $590,000 Project Grant to the University of California Irvine (UC Irvine) on August 15, 2023 under the Biological Sciences program (CFDA 47.074). The goal of this 3-year research project is to develop novel strategies for real-time metabolite sensing and metabolite-induced enzyme localization that can contribute to fundamental cellular knowledge and improve the efficiency of synthetic biology...

This Project Grant award from the National Institute of General Medical Sciences (NIGMS Biomedical Research and Research Training Program, CFDA 93.859) provides $505,387 to The Trustees of Columbia University in the City of New York to acquire a ZEISS LSM 900 with Airyscan 2 confocal microscope system. The state-of-the-art imaging equipment will be used to enhance the capabilities of Columbia University's Advanced Tissue Pathology and Imaging (ATPI) Core to visualize and quantify tissue and...

This Project Grant award from the National Science Foundation (NSF) Integrative Activities program (CFDA 47.083) provides $940,303 to the University of California, Merced (UC Merced) to acquire a state-of-the-art TimsTOF Pro 2 mass spectrometry system coupled to a nano-UPLC liquid chromatography system. This instrumentation will enable advanced biomolecular research into host-microbe interactions at UC Merced, a Hispanic-serving institution located in California's San Joaquin Valley. The...

This $350,000 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) to The Leland Stanford Junior University aims to develop new cryogenic preservation and high-resolution imaging procedures to transform plant cell biology research. The primary objectives are to enable observation of plant cell and tissue ultrastructure in their native state using advanced volume electron microscopy and cryo-electron tomography techniques. This innovative...

This Project Grant award in the amount of $965,755 was provided by the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) to Pennsylvania State University. The funding will support the establishment of a groundwork for large-scale access to synchrotron microCT for 3D high-resolution histotomography, enabling the quantitative characterization of anatomical and microanatomical phenotypes across whole organisms. This includes setting up a pilot imaging...

This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under CFDA Program 93.859 Biomedical Research and Research Training, will provide $417,400 to support the development and advancement of mass spectrometry imaging (MSI) tools to enable more accurate and comprehensive chemical characterization of the glycome (the complete repertoire of cell carbohydrates) at tissue and cellular resolutions. The research aims to overcome current limitations in glycome imaging...

The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $750,000 Project Grant to The Washington University in St. Louis to support research and training related to understanding how metabolic burdens affect microbial cells used in biotechnology applications. The 3-year award, which commenced on August 15, 2023, will enable the Principal Investigator to acquire expertise in modern metabolomics and gene editing techniques, and apply these methods to...

The National Institutes of Health (NIH) Office of Research Infrastructure Programs (ORIP) awarded a $713,643 Project Grant (CFDA 93.351) to The Trustees of Columbia University in the City of New York, Health Sciences Division, to acquire a BD FACSDiscover S8 high-end cell sorter. This specialized instrument combines real-time imaging, full-spectrum detection, and 6-way sorting capabilities, enabling the identification and purification of up to 6 unique cell populations based on morphology,...

Through a $120,000 Project Grant awarded by the Department of Agriculture National Institute of Food and Agriculture under the Agriculture and Food Research Initiative (CFDA 10.310) program, Colorado State University is conducting research to determine the metabolic function of the enzyme phosphoenolpyruvate carboxykinase (PEPCK) and its ability to promote embryo development in bovine in vitro fertilization (IVF) systems. The research aims to elucidate PEPCK's role in sustaining embryo...

This $900,000 Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will support research at the University of Wisconsin-Madison to analyze how cellular recycling processes (autophagy) impact the nutrient efficiency and stress tolerance of different cell types within maize leaves. The key products and services to be delivered under this 2-year award include: Comprehensive molecular analysis of autophagy and nutrient remobilization in...