Project Grant 2015028

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Delaqua Pharmaceuticals, Inc. aims to enhance the therapeutic use of hydrophobic drugs through a polymeric micelle approach to drug solubilization. The key objectives are to 1) improve the formulation of spherical micelles for enhanced stability and drug solubilization, 2) perform initial toxicity studies to establish the safety of the platform, and 3) demonstrate...

This Cooperative Agreement award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program provides $1,250,000 in funding to Biodevek Inc., a Boston-based small business, to develop a sprayable hydrogel sealant for managing gastrointestinal (GI) lesions and bleeding. The project aims to create the first minimally invasive, bio-adhesive hydrogel solution that can provide sustained lesion protection and hemostasis, with the potential to...

Nano Pharmasolutions, Inc. received a $275,961 Project Grant award from the National Science Foundation Division of Industrial Innovation under the Engineering federal grant program (CFDA 47.041). The grant funds the development of a novel nanoformulation drug delivery platform to address challenges associated with poorly soluble drugs. The goal is to improve drug solubility and bioavailability through innovative formulation approaches. The one-year project period runs from August 1, 2021...

This National Science Foundation (NSF) Cooperative Agreement under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $1,016,000 in funding to Nostopharma LLC to develop an innovative, sustained-release, and biodegradable drug delivery platform for localized treatment of post-traumatic injuries. The goal is to create a medication delivery system using anti-inflammatory nanoparticles embedded with a Hedgehog pathway antagonist, arsenic trioxide, to address unmet...

This Cooperative Agreement award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $1,247,672.00 to Superior Nano LLC to develop an oral insulin delivery system using lipid nanoparticles. The goal is to create the first insulin pill for patients with diabetes, which would improve accessibility and adherence compared to injectable insulin. The project aims to optimize the ability of lipid nanoparticles to encapsulate...

Superior Nano LLC received a $512,000 National Science Foundation Project Grant to develop dense nanolipid fluid systems for delivering drugs with poor bioavailability. The NSF funding supports research from June 2022 to May 2023 under the Technology, Innovation, and Partnerships program. This award will allow Superior Nano to advance scientific understanding of surfactant-lipid-water systems and create new knowledge applicable to manufacturing drug nanoparticles using twin-screw extrusion. By...

This three-year project grant from the National Science Foundation Division of Materials Research, totaling $306,307, will fund research into elucidating the rate-limiting steps of biopolymer dissolution and developing new biopolymer derivatives for oral drug delivery systems. Virginia Polytechnic Institute and State University, doing business as Virginia Tech, will lead the collaborative research effort to understand how additives impact the dissolution rates of polysaccharide derivatives....

This $999,783 Phase II Small Business Innovation Research (SBIR) cooperative agreement from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports Intact Therapeutics' development of a thermogel-based drug delivery platform for the treatment of upper gastrointestinal bleeding (UGIB). Intact Therapeutics' proprietary thermogel technology aims to rapidly stop UGIB prior to endoscopic treatment, potentially reducing patient morbidity,...

This federal Project Grant award of $350,027 from the National Institute of General Medical Sciences (NIGMS, CFDA 93.859 Biomedical Research and Research Training) to Asko Therapeutics, Inc. is focused on developing a cost-effective, efficient, and generalizable water-based PLGA microsphere encapsulation technology for delivering commercial peptide drugs. The goal is to create a paradigm-changing, versatile, scalable, and cost-effective technology for monthly injections of peptide drugs,...

Spherofill LLC received a $275,391 National Science Foundation Project Grant under the Engineering program (CFDA 47.041) to develop Porous Walled Hollow Glass Microspheres as a novel sustained drug delivery platform. The one-year award running from June 2021 to May 2022 will support Phase I of Small Business Technology Transfer research into PWHGMs, a flexible platform capable of customized drug release profiles. As part of its mission to promote innovation, the NSF Directorate for Engineering...