The U.S. National Science Foundation awarded a $275,000 SBIR Phase I Project Grant to Om Therapeutics Inc. in La Jolla, CA under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program. The project aims to enable the discovery of new medicines at an unprecedented rate by empowering researchers to conduct drug discovery programs through the generation of massive, empirical, and scalable data on small molecule and protein interactions using machine learning. The key innovation is...
This Cooperative Agreement award, funded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop a bioprocessing system to isolate and purify therapeutic antibodies directly from cell culture. The $999,998 award to Athem LLC, a minority-owned small business, will enable scaling up a novel nanoparticle-based purification media and an automated prototype system. The goal is to simplify the manufacturing of biologics, reduce...
This Project Grant award from the National Science Foundation (NSF) under its Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $275,000 to Tectaria Bio LLC to engineer cell lines with activated proteasomes for increased biomanufacturing efficiency. The project aims to test the feasibility and application of a novel technology to significantly increase the protein production capabilities of cell lines used in the manufacture of biologics, gene therapies, and vaccines....
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Wild Microbes Co aims to develop improved bacterial strains for the cost-effective production of proteins used in detergents, personal care products, and dairy. The project seeks to identify superior bacterial protein production hosts and create advanced genetic engineering tools to maximize the yield, titers, and productivity of these bacterial factories. The advanced...
The National Science Foundation (NSF) awarded a $271,443 Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to Mammae Biosciences, Inc., a minority-owned, for-profit, woman-owned business and manufacturer, to develop an enzymatic method to produce compounds found in human milk at commercial scale. The goal is to assess an affordable enzymatic process for generating marketable natural compounds usually found in human milk, such as N-acetylglucosamine...
The National Science Foundation awarded Ancilia, Inc. a $255,717 Small Business Technology Transfer Phase I Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The grant will support development of phage-resistant bacterial therapeutics from July 2021 through June 2023. The NSF Technology, Innovation, and Partnerships program seeks to advance science, engineering, and technology innovation to address national challenges. Under this award, Ancilia...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Seia Bio Inc., a minority-owned and woman-owned small business in Cambridge, MA, aims to enable the widespread adoption of beneficial microbes. The project will advance the fundamental understanding of how to formulate and protect microbes from common stressors like heat, UV-light, shock, and humidity. This will result in a generalized process to formulate and scale-up...
This NSF SBIR Phase I project, awarded by the National Science Foundation under the Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop a cost-effective and environmentally-friendly enzymatic bioremediation strategy to degrade per- and polyfluoroalkyl substances (PFAS), a class of toxic and bioaccumulating chemicals. The $275,000 award to Revivbio, Inc., a woman-owned small business in Cambridge, MA, supports the use of protein engineering techniques to design enzymes...
The National Science Foundation (NSF) awarded a $1,000,000 Cooperative Agreement under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Oakgrove Bio LLC, a small business located in Talleyville, DE. The award aims to accelerate the commercialization of bioactive and structural peptides by advancing a recombinant technology platform to dramatically reduce the cost of peptide manufacturing. The project leverages the fact that peptides can be treated as polymers rather than...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $274,918 to Cascade Biocatalysts Inc. will fund research and development to demonstrate the commercial feasibility and scalability of a patent-pending approach for stabilizing enzymes through engineered polymer-enzyme interactions. The goal is to enable environmentally sustainable, low-carbon chemical manufacturing processes that utilize enzymes as catalysts, which can decrease...