Project Grant 1819996

This $550,000 Project Grant awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program supports the development of a remote monitoring system to reduce infections among patients undergoing peritoneal dialysis (PD). The project aims to enable real-time, continuous, and quantitative monitoring of biomarkers in dialysate to facilitate early detection and diagnosis of PD-associated infections. To achieve this, the project team will:...

The National Institute of Diabetes and Digestive and Kidney Diseases awarded Pavaj Vascular Corporation $1,094,070 on September 2, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop and advance nanoparticle-mediated drug delivery technology for preventing arteriovenous fistula stenosis in hemodialysis patients. Pavaj Vascular is engineering a therapy using poly(lactic-co-glycolic acid) nanoparticles encapsulated with calcitriol—the...

Starlight Cardiovascular, Inc. was awarded a $1,477,713 Project Grant from the National Heart, Lung, and Blood Institute's Cardiovascular Diseases Research program to develop the first FDA-approved stent designed specifically for ductus arteriosus. The ductus arteriosus is a natural blood vessel that remains open in infants born with certain congenital heart defects; currently there are no stents approved for this use, forcing clinicians to repurpose adult coronary stents which have a high 47%...

The National Institute of Diabetes and Digestive and Kidney Diseases awarded Angiograft LLC $314,081 on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop acellular tissue-engineered vascular grafts (ATEVs) for dialysis access applications. Angiograft will establish the feasibility of engineered collagen-based ATEV grafts constructed from small intestinal submucosa functionalized with cross-linked heparin by testing them...

This federal Project Grant award for $220,000, provided by the National Science Foundation's (NSF) Division of Mathematical Sciences under the Mathematical and Physical Sciences program (CFDA 47.049), aims to deliver a comprehensive mathematical and computational framework for optimizing the design of next-generation stents. Key products and services to be provided under this 3-year award (August 1, 2024 to July 31, 2027) include: Developing a reduced model optimization module for the optimal...

The National Heart, Lung, and Blood Institute awarded Perfusion Solutions Inc. $217,013 on August 1, 2026, to develop a bearingless, fail-safe pump for patients with single ventricle physiology following Fontan surgical palliation under the Cardiovascular Diseases Research program (CFDA 93.837). The award funds Phase I research to design and develop a bearingless motor integrated into a centrifugal pump rotor, with the pump's stator incorporating the motor stator. The device is engineered to...

The National Heart, Lung, and Blood Institute awarded Pediastent LLC $1.472 million on August 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct a first-in-baby clinical study of the CARDIAZN bioresorbable stent, a zinc-alloy device designed to treat pulmonary artery stenosis and coarctation of the aorta in small children. The CARDIAZN stent maintains peak radial strength for approximately six months post-implantation to provide structural support to diseased...

This $136,924 National Science Foundation project grant supports the development of a smart stent for post-endovascular aneurysm repair surveillance at the University of South Florida. The key product to be delivered is a flexible, battery-less bioelectronic stent system that combines piezoelectric porous membrane sensors and microcoils for near-field magnetic induction communication. The smart stent will be woven with sensors inside and outside of a conventional stent graft to enable wireless...

The National Heart, Lung, and Blood Institute awarded Aust Development, LLC a Phase I Small Business Innovation Research project grant of $626,604 on September 15, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837). Aust Development will develop a novel 3D pre-shaped delivery catheter platform to enable precise identification and safe delivery of cardiac conduction system pacing leads. The delivery system will allow physicians to sequentially map the septal myocardium, fix...

This $274,547 Project Grant awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program aims to develop a novel Aneurysm Sealing Device (ASD) for endovascular treatment of Abdominal Aortic Aneurysms (AAA). The project seeks to create a device that can completely seal the aneurysm sac, reducing the risk of post-procedure complications and the need for repeat interventions. Key objectives include validating the device's adaptability...