Project Grant 1807371

Cache DNA, Inc. was awarded a $255,819 National Science Foundation Technology, Innovation, and Partnerships Project Grant to develop a massively scalable storage solution for nucleic acids using barcoded polymer packets. The goal of the Phase I Small Business Innovation Research project is to establish a low-cost approach to maintaining the integrity of nucleic acids, including animal, bacterial, and viral genomes, at room temperature for decades without requiring energy-intensive freezing or...

This $600,000 Project Grant from the National Science Foundation's Computer and Information Science and Engineering program will fund research at the University of Texas at Austin to develop DNA-based storage and computation techniques. Specifically, the award supports the creation of a "SIMD-DNA" paradigm that uses strand displacement reactions to manipulate digital data encoded in the topological structure of DNA. This approach aims to enable parallel, in-memory computation without...

This three-year, $930,252 Project Grant from the National Science Foundation's Division of Computing and Communication Foundations, under the Computer and Information Science and Engineering program, will support research exploring applications of digital microfluidic technology for DNA storage, computation, and synthetic biology. A team from the University of Minnesota will leverage an electronic platform developed by industrial partner Seagate to manipulate droplets and assemble DNA at...

This $300,000 Project Grant from the National Science Foundation's Division of Computer and Network Systems, under the Computer and Information Science and Engineering program (CFDA 47.070), will support research to develop efficient ways to enlarge practical DNA storage capacity by integrating bio-computer technologies. Led by researchers at the University of Minnesota, the interdisciplinary team will investigate approaches to improve the scalability of DNA storage, including identifying more...

The National Science Foundation (NSF) awarded a $283,362 Project Grant under the Computer and Information Science and Engineering (CISE) program to the University of Texas at Dallas (UTD) to develop innovative approaches for expanding the practical capacity of synthetic DNA storage. The project aims to address key technical challenges that currently limit the scalability of DNA-based archival storage, which has the potential to preserve the growing volume of digital data worldwide for hundreds...

The National Science Foundation awarded $375,000 under the Mathematical and Physical Sciences program (CFDA 47.049) to Boise State University for the project "SEMISYNBIO-III: Scalable Nucleic Acid Memory." The three-year project aims to advance DNA-based information storage through algorithms, imaging, and synthetic biology techniques. Specifically, the university will develop rotation-invariant data encoding and error correction, deep learning for image processing, and Bayes-optimal...

This $375,000 project grant from the National Science Foundation's Division of Computing and Communication Foundations, under the Computer and Information Science and Engineering program (CFDA 47.070), will support the development of hybrid cell-semiconducting polymer systems for high-density biological data storage at William Marsh Rice University. Over the two-year period from August 2022 to July 2025, the university researchers will work to encode 100 bytes of information into synthetic RNA...

Sequegenics LLC received a $251,073 Project Grant award from the National Science Foundation Division of Industrial Innovation under the Engineering federal grant program (CFDA 47.041). The grant supports development of low-cost and scalable methods for creating genomic databases using long-read next-generation DNA sequencing technologies. This aligns with the program's goals of fostering innovation in engineering research. The one-year project period runs from August 1, 2021 through July 31,...

Armonica Technologies, Inc. was awarded a $1,047,600 Project Grant from the National Human Genome Research Institute of the Department of Health and Human Services to develop a novel DNA sequencing platform. The award was made under the Human Genome Research program (CFDA 93.172), which supports technologies to accelerate genomic research and its application to human health. Specifically, Armonica will use the funding to optimize a metal-insulator-metal structure for single base sensitivity...

The National Science Foundation awarded a $300,000 project grant to the University of Texas at Dallas under the Engineering program (CFDA 47.041) for a project period of February 15, 2023 through January 31, 2025. The award will support the development of a secure DNA storage system using physically unclonable functions and CRISPR technology. Specifically, the university researchers will investigate using cell lines for distributed information storage and characterize genomic locations for...