This three-year, $930,252 Project Grant from the National Science Foundation's Division of Computing and Communication Foundations, under the Computer and Information Science and Engineering program, will support research exploring applications of digital microfluidic technology for DNA storage, computation, and synthetic biology. A team from the University of Minnesota will leverage an electronic platform developed by industrial partner Seagate to manipulate droplets and assemble DNA at megahertz speeds, closing gaps between theoretical and demonstrated reading/writing capabilities. Specifically, the team will explore performing computation on DNA strands using topological modifications like nicks and toeholds, assembled directly on the electronic grid, rather than in nucleotide sequences. They will also examine applications in synthetic biology like cell-free protein expression, liposome encapsulation, and RNA engineering on the grid. This award reflects NSF's mission to support merit-reviewed projects advancing computing and information sciences, with the potential for intellectual merit and broader impacts.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $930.3k | 8/25/22 |