Project Grant 1647712

This $274,786 Phase I Small Business Innovation Research (SBIR) award from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) will fund the development of a cutting-edge scanning magnetometer microscope by Femtosenselabs, LLC. This new microscope technology will enable high-resolution imaging of novel magnetic materials with unprecedented sensitivity at the nanoscale, supporting the advancement of spintronics and the development of...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Small Business Innovation Research (SBIR) Phase I project award of $274,998 to Magnify Biosciences Inc. aims to develop an automated "AutoMagnify" device that physically expands biological specimens up to 1,000 times in 3D while preserving spatial and molecular integrity. This advancement will enable conventional light microscopes to achieve nanoscale imaging resolution capabilities...

Federal Grant Award Summary Atomnaut Inc. received a $305,000 Small Business Innovation Research (SBIR) Phase I Project Grant from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) awarded June 1, 2025, with completion targeted for May 31, 2026. The company will develop and validate a novel microscope sample vessel technology that enables in situ vitrification—the freezing of biological samples directly on the microscope stage rather...

This $1.1 million Project Grant from the National Science Foundation's Mathematical and Physical Sciences program will fund the acquisition of a magnetic-field-free atomic-resolution scanning transmission electron microscope at the University of Illinois at Chicago from September 2022 through August 2025. The microscope's novel lens design provides a magnetic-field-free sample region allowing for atomic-resolution imaging and chemical analysis of quantum materials such as magnetic,...

This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I project awarded to 3Fates-Xray, Inc. aims to develop a deep learning approach to enable "single-shot" X-ray phase-contrast imaging. This technology has the potential to significantly enhance the capabilities of next-generation X-ray imaging systems for applications such as aviation security, food inspection, and additive manufacturing quality control. The $274,996 award, which runs from Sep 1, 2023...

This $275,000 Small Business Innovation Research (SBIR) Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program supports the development of a label-free, high-resolution, high-throughput protein screening platform called Vibrational Spectroscopy with Metasurface Optics (VISMO). The technology aims to enable simultaneous, minute-scale measurement of millions of protein samples, which would dramatically improve the lengthy and costly cycles...

This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $349,999 to Denovx, LLC to adapt the company's surface science approach to improving protein crystallization for enhancing cryogenic electron microscopy (cryo-EM) specimen quality. The goal is to identify physical and chemical modifications to cryo-EM support materials that can enhance the adsorption and random orientation of...

This $388,983 federal Project Grant award from the National Science Foundation (NSF) Division of Chemistry's Chemical Measurement & Imaging Program and Chemistry of Life Processes Program supports the development of a new optical microscope by Professor Eric Potma at the University of California, Irvine. The instrument leverages chiral sum-frequency generation (SFG) microscopy to visualize protein structures in cells and tissues without the need for chemical labeling. This label-free imaging...

This National Science Foundation Project Grant of $255,261 awarded under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) will fund the development of optimized extraction and projection optics for ion point sources. Steam Instruments Inc. will demonstrate technology advances in imaging mass spectrometry through this Small Business Innovation Research Phase I project. Specifically, the company aims to markedly improve mass resolving power to separate key mass...

The National Science Foundation Division of Chemistry awarded Columbia University a $442,564 Project Grant under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to develop new microscopy techniques for imaging ultrafast chemical transformations between molecules separated by large distances. Principal Investigator Milan Delor and his research group will leverage polaritons, which are part-light part-matter particles, to significantly increase the sensitivity of optical...