Project Grant 1416369

This $448,818 Project Grant awarded by the National Science Foundation (NSF) under the Engineering program (CFDA 47.041) aims to develop a miniaturized, sensitive, and user-friendly electromagnetic (EM) sensing platform for rapid bacterial diagnostics. The project leverages integrated circuit (IC) chips and microfluidic integration to create a portable system capable of distinguishing bacterial phenotypes and detecting strain-specific surface biomarkers. Key innovations include: 1)...

Under a $997,781 cooperative agreement awarded by the National Science Foundation (NSF) through its Technology, Innovation, and Partnerships (CFDA 47.084) program, Nanopath Inc. - a woman-owned small business - is developing an integrated point-of-care system for rapid pathogen identification and characterization. The system utilizes proprietary nanosensor technology to detect target nucleic acid sequences directly from patient samples, eliminating the need for bacterial culture or nucleic...

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $257,807 Project Grant (CFDA 93.286) to the University of California, San Diego (UCSD) to develop a living biosensor technology for rapid, low-cost DNA diagnostics. The proposed project aims to create a hybrid living biosensor/lateral flow assay that can detect and analyze DNA sequences in raw samples without extensive purification. The biosensors will leverage bacterial competence and CRISPR-Cas systems to...

The National Science Foundation (NSF) awarded a $274,750 Small Business Innovation Research (SBIR) Phase I grant to Amplified Sciences Inc. on March 15, 2024 under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program. The project aims to develop a surface-enhanced Raman spectroscopy (SERS)-based diagnostic platform to detect and monitor multiple inflammatory biomarkers associated with various cancers. Key objectives include: 1) synthesizing ultrasensitive SERS-active dye...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $298,646 to Anvil Diagnostics Inc., a minority-owned small business located in Cambridge, MA, is for the development of a rapid, ultra-sensitive, and multiplexed diagnostic test for detecting sepsis-causing pathogens in neonates. The proposed DNA-based technology aims to comprehensively identify and quantify a wide range of pathogens from small blood volumes in under 4 hours, a...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Quarksen LLC provides funding to develop an affordable, point-of-care diagnostic device for detecting viral and non-viral sexually transmitted infections (STIs) such as chlamydia, gonorrhea, syphilis, HIV, hepatitis C, and trichomoniasis. The project aims to create a device with an array of sensors that can rapidly and accurately detect STI biomarkers from cervical...

This Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $305,000 to Resonantia Diagnostics, Inc. to develop a transformative point-of-care diagnostic platform capable of rapidly identifying pathogens and determining their antimicrobial susceptibility. The project aims to achieve three key technical objectives: (1) demonstrating accurate antimicrobial susceptibility testing at very low pathogen loads, (2)...

This Project Grant award from the National Science Foundation's Integrative Activities (IA) program provides $275,000 to Clemson University to develop a flexible, tunable voltammetric sensor that can rapidly detect and quantify virulence signals from the Pseudomonas aeruginosa bacteria. The goal is to enable faster determination of infections caused by antibiotic-resistant bacteria, which annually lead to more than 35,000 deaths in the U.S. despite widespread antibiotic availability. The...

This National Science Foundation (NSF) Biological Sciences grant award provides $2,225,964 to the Georgia Tech Research Corporation (Georgia Tech) to develop a novel biosensing platform called "protocell communities" that can be used for rapid, low-cost medical diagnostics. The project aims to create a tool that can diagnose medical conditions by detecting and integrating multiple indicator molecules, addressing limitations of single-analyte diagnostics. The protocell technology uses...

This National Science Foundation (NSF) Partnerships for Innovation - Research Partnerships (PFI-RP) project grant, CFDA #47.084, provides $549,649 to the University of Rochester to advance the development of a novel membrane-based sensor technology for the rapid and specific detection of infectious pathogens in biofluids. The project aims to integrate the membrane sensor into a hand-operated microfluidic device with a colorimetric readout, and demonstrate the generalizability of the approach...