Project Grant 1249008

This SBIR Phase I project, awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, is focused on the development of a novel mammalian cell-based nano-biological coating for implantable medical devices. The goal is to address the critical health and economic burden associated with implant-related infections by reducing or eliminating them through the use of this biocompatible and antimicrobial nano-biological coating. The $305,000...

Karios Technologies LLC, a for-profit organization, received a $274,954 SBIR Phase I grant from the National Science Foundation (NSF) Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a novel, ready-to-use, large volume delivery system for in situ forming biomaterials. The biomaterials are intended to serve as tissue sealants, scar tissue reducers, and vehicles for drug or cell delivery during surgical procedures. The project aims to transfer a proprietary biomaterial...

The National Science Foundation (NSF) awarded a $273,563 Small Business Innovation Research (SBIR) Phase I grant to Medicarbone Inc. under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program. The objective of this 12-month project is to design, develop, and demonstrate the feasibility of a minimally-invasive intramedullary (IM) sleeve system with an in situ, photocurable, and removable polymeric bone cement for the treatment of orthopedic fractures. The project aims to address...

Nostopharma LLC was awarded a $256,000 Small Business Technology Transfer Phase I Project Grant from the National Science Foundation to develop a sustained-release, biodegradable nanoparticle drug delivery system for treatment of soft tissue trauma complications. Funded under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the 12-month project beginning March 1, 2022 aims to demonstrate in vitro and in vivo feasibility of modulating the ectopic bone microenvironment...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) grant, awarded to Tissueform, Inc., a for-profit woman-owned small business in Boulder, Colorado, aims to develop a library of human-based bioinks for 3D bioprinting applications. The $274,822 award, with a performance period from September 2024 to August 2025, will focus on creating granulated bioinks for tissues such as cartilage, bone, skin, liver,...

This $476,886 federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports research at Boston University to develop computational models for predicting the spatiotemporal distribution of growth factors in tissue engineering scaffolds. The goal is to optimize scaffold designs to achieve optimal growth factor exposure profiles that improve tissue regeneration outcomes, particularly for cartilage repair. The research utilizes reaction-diffusion...

This STTR Phase I Project Grant, awarded by the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships program), provides $305,000 to Magsorbeo Biomedical Corp to develop a bioabsorbable magnesium alloy for maxillofacial fixation implants. The goal is to create a magnesium-based implant that can temporarily support healing, then gradually be absorbed by the body, eliminating the need for secondary removal surgeries. This innovation aims to improve healthcare...

This Project Grant awarded by the National Science Foundation (CFDA 47.041 - Engineering) to Cleveland State University (CSU) provides $500,000 in funding from January 1, 2025 to December 31, 2027 to develop bioprinted tissue scaffolds with Schwann cell density gradients and electrical conductivity for peripheral nerve regeneration. The goal is to understand how Schwann cell density gradients and electrical properties within the scaffolds can enhance the regeneration of injured peripheral...

The National Science Foundation awarded a $256,000 Small Business Technology Transfer Phase I Project Grant to Multiscale Integrated Technology Solutions LLC of Indianapolis, Indiana. The grant supports research and development of enhanced composite materials through interlaminar incorporation of carbon nanotube/epoxy nanoscaffolds using genetic algorithm assisted machine learning and neural networks. This award advances the goals of the NSF Directorate for Engineering's CFDA 47.041...

This SBIR Phase I project, awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), aims to develop novel, sustainable textile fibers and fabrics derived from seaweed biopolymers and nanomaterials. The project seeks to create a plastic-free, multifunctional textile material with enhanced properties such as fire resistance, UV protection, and heat shielding, which can serve as an alternative to fossil fuel-based textiles....