Formula Grant 0000003B1GUSAPT

This $673,500 Project Grant from the National Institutes of Health's National Institute on Alcohol Abuse and Alcoholism will fund Amygdala Neurosciences, Inc. to develop new, potent, selective, and reversible inhibitors of aldehyde dehydrogenase 2 (ALDH2) for the treatment of alcohol use disorder. The goal is to implement an innovative screening technology to discover novel compounds that reduce craving and alcohol consumption by selectively inhibiting ALDH2 in a reversible manner, avoiding...

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $537,587 Project Grant under the Alcohol Research Programs (CFDA 93.273) to The University of Texas Southwestern Medical Center to conduct research on the metabolic consequences of liver inflammation on alcohol consumption and alcohol-associated liver disease (ALD). The key objectives are to identify the mechanisms by which the transcription factor IRF3 suppresses the expression and secretion of the metabolic regulator...

This $250,000 Project Grant award from the National Center for Injury Prevention and Control, part of the Centers for Disease Control and Prevention, supports the Drug-Free Communities (DFC) Support Program (CFDA 93.276). The award will fund a 5-year initiative by the Orange County Council On Alcoholism, Inc., doing business as the Alcohol And Drug Awareness Council Of Orange County, to establish and strengthen a community coalition focused on preventing and reducing youth substance use in the...

This $750,000 Project Grant award under the Substance Abuse and Mental Health Services Projects of Regional and National Significance (CFDA 93.243) program, administered by the Substance Abuse and Mental Health Services Administration (SAMHSA), supports Children's Hospital Los Angeles (CHLA) in implementing the Strategic Prevention Framework - Partnerships for Success initiative. The key products and services to be delivered include: Building the capacity of a multi-sector coalition in the...

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $438,375 Project Grant under the Alcohol Research Programs (CFDA 93.273) to Cedars-Sinai Medical Center to establish a human liver-on-a-chip model for studying alcohol-associated liver disease (ALD). The 2-year project, starting September 2023, aims to investigate the roles of liver sinusoidal endothelial cells and acetaldehyde metabolism in regulating ethanol-induced liver damage as well as the contribution of fibrotic...

This federal Project Grant award, funded by the Executive Office of the President's Office of the National Drug Control Policy under the Congressional Directives program (CFDA 95.010), provides $4,400,000 to implement special Congressionally-directed substance use disorder prevention, treatment, and community-based health initiatives. The primary awardee, the University of Mississippi, will use the funds to support a range of projects focused on mental health services, substance abuse...

This Project Grant award of $120,000, provided by the U.S. Department of Health and Human Services Substance Abuse and Mental Health Services Administration (SAMHSA) under the Substance Abuse and Mental Health Services Projects of Regional and National Significance (CFDA 93.243) program, supports the "Prevention Works: A Community Collective to Address Underage Alcohol Use and Binge Drinking in Throggs Neck, Bronx NY" project implemented by the Archdiocese of New York's Archdiocese...

The Substance Abuse and Mental Health Services Administration (SAMHSA) awarded a $120,000 Project Grant under the Substance Abuse and Mental Health Services Projects of Regional and National Significance (CFDA 93.243) program to the Youngstown Urban Minority Alcoholism And Drug Abuse Outreach Program, Inc. (Youngstown Umadaop) to implement the Thrive Without Drinking (TWD) Project. The TWD Project will implement evidence-based prevention strategies in Youngstown, Ohio to prevent and reduce...

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) awarded a $330,829 Project Grant under the Alcohol Research Programs (CFDA 93.273) to the Board of Regents of the University of Nebraska, University of Nebraska Medical Center (UNMC) Division. The grant, titled "Leveraging Alcohol Use Disorder Screening for Treatment in Routine Perioperative Care: ALLUSCARE", aims to leverage existing electronic health record-integrated alcohol screening tools to increase the provision of...

This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $242,310 to Wake Forest University Health Sciences to conduct research on the effect of ethanol self-administration on cocaine reinforcement in male and female monkeys. The aims of the research are to: 1) characterize the effects of ethanol on vulnerability to cocaine reinforcement, 2) examine how ethanol influences maladaptive cocaine choice in...