Cooperative Agreement UG3AR085896
- The federal Project Grant award of $649,391 provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) is supporting research to enhance healing after injury. The overarching objective is to define the mechanisms that restrain tissue regeneration in order to develop new therapeutics to improve healing of the gut and skin following injury or infection. The 5-year project, which...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $2,070,827 Project Grant under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846) to the Icahn School of Medicine at Mount Sinai. This grant aims to identify novel microbial factors that can enhance wound repair, a significant public health issue with over 100 million new acute skin wounds annually and substantial treatment costs exceeding $25 billion. The...
- This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), provides $296,256.00 to Advanced Molecular Healix Inc. to develop and test novel mRNA therapeutics for enhancing pedicle flap healing. The research aims to quantify the expression and effects of hypoxia-inducible factor 1-alpha (HIF-1α) mRNA when delivered via lipid nanoparticles, both in...
- This Project Grant award of $169,344 was provided by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The award supports research at the University of California, Davis to investigate the role of inflammation and immunomodulation in fracture healing in the context of polytrauma. The key objectives are to: (1) characterize the upregulation of inflammatory cytokines and innate...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $1,829,773 project grant under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) to the University of Florida. The grant, awarded on September 5, 2025, will fund research to investigate the mechanisms by which sepsis harms muscles and impedes proper regeneration, with the goal of developing new strategies to improve septic patients' recovery of skeletal muscle function...
- This $546,159 Project Grant awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research Federal Grant Program (CFDA 93.846) will support a cross-sectional observational study on the relationship between foot biomechanics, metatarsal structure, and running footwear in athletes with bone stress injuries. The study will evaluate associations between foot biomechanics, intrinsic foot muscle size and...
- This $190,137 Cooperative Agreement was awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The agreement aims to bridge the gap between genetic testing and patient care for muscular dystrophies and myopathies by defining the clinical relevance of genes and genetic sequence variants associated with these disorders. Key efforts include evaluating the clinical validity of...
- The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) awarded a $596,189 project grant to Rush University Medical Center in Chicago, Illinois under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant aims to develop comprehensive preclinical testing strategies and further elucidate the factors contributing to in vivo fretting-corrosion damage and adverse local tissue reactions within modular junctions of total joint replacements....
- The University of Southern California (USC) received a $628,174 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846). The purpose of this multi-year grant, with an ultimate completion date of March 31, 2030, is to support research into the cellular origins and molecular mechanisms underlying the development of arthrofibrosis, a debilitating...
- This federal Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846), is intended to elucidate the effects of blood and blood-derived components on meniscus tissue homeostasis, repair, and post-traumatic osteoarthritis development. The $487,652 award to Duke University will fund research to investigate the mechanisms by which blood-derived immune...
This federal Cooperative Agreement award, funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports research to evaluate the efficacy of accelerated flap coverage versus standard timing in the treatment of severe lower extremity musculoskeletal injuries. The $267,527 award, which commenced on September 10, 2025, aims to determine if early flap surgery (within 72 hours of injury) can reduce infection rates compared to the current standard of care with a 10-day average time to flap surgery. The Johns Hopkins University, a leading federal research institution, is the awardee and will conduct this study to provide evidence to motivate changes in clinical practice and improve outcomes for patients with these severe injuries.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $267.5k | 9/8/25 |