Cooperative Agreement U58DP005418

This Project Grant award of $543,221.00 from the National Cancer Institute (NCI) under the Cancer Biology Research program (CFDA 93.396) is supporting research at the Albert Einstein College of Medicine to better understand the cellular and molecular mechanisms driving lineage plasticity in basal-like breast cancer (BLBC). The key objectives are to: 1) Define the critical de-differentiated cell states involved in BLBC progression and explore strategies to target these cells for cancer...

This Cooperative Agreement award for $703,321.00, provided by the National Cancer Institute (NCI) under the Cancer Cause and Prevention Research federal grant program (CFDA 93.393), will support the adaptation and implementation of an evidence-based patient navigation intervention for adolescent and young adult (AYA) cancer survivors. The project aims to improve coordination of care, including surveillance for cancer recurrence, management of long-term effects, and delivery of preventive and...

This federal Project Grant award from the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) will fund a $717,786 study to evaluate the efficacy of a tailored medication adherence-promotion intervention called SUMMIT for adolescents and young adults (AYAs) with cancer. The study aims to improve medication adherence among AYAs, who often struggle with adherence, leading to poor health outcomes like relapse and death. The Children's Hospital Medical Center in...

This Project Grant award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) provides $527,159 in funding to Brigham & Women's Hospital, a subsidiary of Partners Healthcare System, to conduct research on the role of DNA damage and cell fate plasticity in the initiation of BRCA1-related basal-like breast cancer. The key objectives of the research are to: 1) study whether BRCA1-deficient luminal mammary cells acquire a fetal mammary stem cell-like gene expression program...

This $858,166 Project Grant awarded by the National Cancer Institute (CFDA 93.393 - Cancer Cause and Prevention Research) is for a randomized trial of a targeted palliative care intervention for patients with metastatic breast cancer. The grant supports a 5-year study to be conducted by The General Hospital Corporation (Massachusetts General Hospital) to improve documentation of end-of-life care preferences, delivery of end-of-life care, and patient-reported outcomes for this patient population....

This Project Grant award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) provides $700,690.00 to Health Research, Inc. in Buffalo, NY to support research aimed at deciphering the molecular mechanisms of breast cancer bone metastasis. The 5-year project (04/01/2025 - 03/31/2030) seeks to unravel the biological transition from early-stage microscopic bone metastases to established macro-bone metastases, with a focus on understanding the role of the YAP/TAZ...

This federal Project Grant award from the National Cancer Institute (CFDA 93.393 Cancer Cause and Prevention Research program) provides $651,859 to the Ann & Robert H Lurie Children's Hospital of Chicago to conduct the "#AYAOSM: An Influencer-Driven Social Media Intervention for Oral Chemotherapy Adherence" research project. The 5-year project aims to develop and evaluate a social media-based intervention to improve oral chemotherapy adherence among adolescents and young adults...

This federal Project Grant award, with a total funding amount of $882,470, was provided by the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) to Baylor College of Medicine, a prestigious private non-profit health sciences university in Texas. The primary objective of this 5-year award is to expand the awardee's role as a leader in the design and conduct of NCI-funded clinical trials for children, adolescents, and young adults with cancer, particularly hematologic...

This Project Grant award from the National Cancer Institute (CFDA 93.398 Cancer Research Manpower) provides $197,414 to Rutgers, The State University of New Jersey to conduct research on "Dyadic and Social Network Influences on Health and Well-Being Among Young Adults with Cancer". The award will support the grantee's training goals over a 5-year period from August 7, 2025 to July 31, 2030. Key objectives include enhancing the grantee's expertise in dyadic functioning of young adult...

This Project Grant award of $109,076 from the National Cancer Institute's Cancer Research Manpower program (CFDA 93.398) supports research to identify patterns of gene deletions in metastatic breast cancer. The award, which runs from January 21, 2026 to July 31, 2029, aims to leverage machine learning techniques and comprehensive autopsy data to create a detailed landscape of genomic evolution in late-stage metastatic disease. The research, conducted by the University of Pittsburgh, seeks to...