Cooperative Agreement U42OD039882
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded $584,232 to Renovate Biosciences Inc. on September 25, 2025, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). Renovate Biosciences will generate human livers from donor patient-specific cells using pigs as bio-incubators. Following technical validation, the work will establish a pathway for producing on-demand transplantation-ready hepatocytes for cellular therapies and...
- The National Institutes of Health Office of the Director awarded a Cooperative Agreement of $554,674 to Temple University on April 20, 2026, to develop and validate a multiorgan microphysiological platform for discovering and screening therapeutics to treat radiation-induced vascular injury. The award is made under the Trans-NIH Research Support program (CFDA 93.310). The recipient will integrate microfluidic models of the blood-brain barrier, gut, and lung into a multiorgan RadChip platform...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Northwestern University $811,941 on September 3, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop three-dimensional intestinal organoid models that investigate the bidirectional relationship between HIV transcription and intestinal barrier function in people living with HIV. The research uses complementary organoid platforms: patient-derived organoids isolated...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Washington $839,388 on August 15, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop engineered human liver tissue for heterotopic transplant and therapeutic rescue of liver disease. The project addresses the critical shortage of donor organs for patients with end-stage liver disease by developing cultured human hepatocytes as organoids that...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Tennessee $639,022 on September 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847, Assistance Type: Project Grant). The award funds a one-year research study designed to promote HIV-to-HIV kidney transplantation as standard-of-care clinical practice in the new regulatory environment following November 2024 modifications to transplant eligibility...
- The National Institutes of Health National Center for Advancing Translational Sciences awarded Intero Biosystems Inc. $349,824 on July 15, 2026, for a Phase I Small Business Innovation Research project to develop a human peristaltic intestinal organoid platform for drug discovery and preclinical testing in gastrointestinal motility disorders. The recipient will engineer and validate a scalable human peristaltic intestinal organoid (peristaltic-HIO) platform that integrates organ-level...
- The National Institutes of Health Office of the Director awarded Baylor College of Medicine a cooperative agreement totaling $560,175 on April 15, 2026, under the Trans-NIH Research Support program (CFDA 93.310) to establish human intestinal organoids as an in vitro model for gastrointestinal acute radiation syndrome. The recipient will develop and optimize human intestinal organoids using high-content imaging to assess the therapeutic potential of a microbial-based medical countermeasure...
- The National Institutes of Health Office of the Director awarded The Medical College of Wisconsin, Inc. $1,555,944 on July 15, 2026, under the Research Infrastructure Programs (CFDA 93.351) to maintain and extend the Hybrid Rat Discovery Panel (HRDP) as a renewable genetic resource for the research community through April 30, 2030. The award funds four core activities: maintaining the HRDP as living colonies comprising 33 classic inbred rat strains, 30 HXB/BXH recombinant inbred strains, and...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded New York University $872,273 on August 20, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to identify modifiable process delays in deceased donor kidney allocation through process mining analysis. The project applies process mining methodology to discover actual kidney placement workflows from data logs at multiple organ procurement organizations (OPOs). The research...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Pennsylvania $712,100 on May 20, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop and characterize human adrenal organoids derived from induced pluripotent stem cells as a platform for understanding adrenocortical functional zonation and testing therapeutic approaches to adrenal diseases. The funded research establishes the first human...
The National Institute of Diabetes and Digestive and Kidney Diseases, an arm of the Department of Health and Human Services National Institutes of Health, awarded a cooperative agreement to the National Disease Research Interchange (doing business as Human Biological Data Interchange) on August 1, 2026, to support the Human Tissue and Organs for Research Resource (HTORR), a project-driven biospecimen collection program providing human organs, tissues, anatomical structures, fluids, and cells to principal investigators studying human biology and disease across all body systems. HTORR operates through a 360 feedback model built on three foundational pillars: scientific support, sample diversity, and career development of principal investigators. The program advances its tissue collection framework by gathering continuous feedback across these pillars and evolving in tandem with NIH high-priority scientific needs and emerging experimental methodologies. HTORR enables researchers from multiple disciplines to utilize human biospecimen-derived experimental model systems to study organ, tissue, and cellular function, and provides state-of-the-art research services supporting new discoveries in human biology, physiology, and disease. The award obligates $250,000 with a period of performance from August 1, 2026, to April 30, 2031. Work is performed in Philadelphia, Pennsylvania. The National Disease Research Interchange is a Philadelphia-based 501(c)(3) non-profit organization specializing in human tissue procurement, pathology, and transportation services for biomedical research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $250.0k | 7/30/26 |