Maintenance and enhancement of the asian american enriched cohort

Active Cooperative Agreement Awarded Last action

Award ID
U24ES036002
Recipient
Awarding agency
Obligated
$817,293

Award facts

Assistance listing
93.113 Environmental Health
Completion date 43% complete
Place of performance
New York, NY 10016, USA

Award details come from USAspending.gov.

Description

As the agency reported it.

Abstract
Over 90% of asian american (ASA) adults are either first-generation (foreign-born) or second-generation immigrants, experiencing a substantial environmental and sociocultural transition in this country. Yet, most environmental epidemiology cohorts have rarely included sufficient numbers of ASA. The famili (food and microbiome longitudinal investigation), is the only large environmental epidemiology cohort, incorporating a broad spectrum of ASA. We uniquely capture environmental, diet acculturation, and sociocultural factors-pre and post-immigration at baseline, and with repeated assessments during follow-up. A biobank, including buccal and stool samples, will greatly advance biological discoveries in the oral and GUT microbiomes, metabolomics, human genomics, and other omics markers. Lastly, the famili represents an exceptional opportunity to compare risk associations in chinese and korean americans, with those in their native countries, through well- established chinese and korean cohort studies in the asia cohort consortium, providing valuable insight into asian ancestry, migration, and health outcomes. The overarching rationale for famili is to examine from an "exposome" perspective, the biological, lifestyle, behavioral, environmental, and sociocultural factors that impact the ASA health disparities, with the ultimate goal of improving ASA health. Initiated in 2018, we completed an initial recruitment and biospecimen collection of 12,000 study participants (aged 35-75 years), including 5,000 ASA. Through this U24, we propose to maintain famili data and biospecimens and enrich the cohort through additional recruitment, data collection, biorepository, data management collaboration, and enhancing workforce diversity. The famili was a unique nationwide resource with extensive data and biospecimen collection to answer important scientific questions advancing environmental health science relevant to niehs strategic plan, including the microbiome, the exposome, individual superstability, and data science/big data. These questions include critical windows of environmental changes through the immigration experience in the new country, racial disparities, and the factors underlying the increase in health outcomes. The famili with integrated community participation will be a foundation to translate knowledge into action regarding disparities in ASA, the often marginalized and underserved population, and further foster collaborations and bring workforce diversity for underserved populations.

Transactions

Action Obligated Date
Amendment Maintenance and enhancement of the asian american enriched cohort - over 90% of asian american (ASA) adults are either first-generation (foreign-born) or… $393,543
Original award $423,750

Quick answers

Who received award U24ES036002?

U24ES036002 was awarded to New York University by National Institute of Environmental Health Sciences (National Institutes of Health) on September 6, 2024.

How much is award U24ES036002 worth?

$817,293 has been obligated on U24ES036002.

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