Cooperative Agreement U24DC022542
- This $647,518 Project Grant award, provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program, supports research investigating the impact of cochlear synaptopathy on brainstem mechanisms of monaural temporal processing and binaural hearing. The study aims to understand the neural mechanisms and loci in the auditory system that produce listening difficulties, which can emerge...
- This federal Project Grant award of $781,703, awarded by the National Institute on Deafness and Other Communication Disorders (NIDCD) under CFDA 93.173 "Research Related to Deafness and Communication Disorders", supports research to better understand sensory development in human cochlear organoids. The goals are to define the developmental trajectories of key sensory cell types, test methods to increase the number of hair cells, and accelerate the maturation of hair cells and sensory...
- This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), provides $767,494 to the University of Miami to develop human inner ear organoid platforms for studying genetic hearing loss and vestibular disorders. The key objectives are to: 1) establish and optimize human induced pluripotent stem cell-derived 3D inner ear organoid systems from patients with...
- The National Institute on Deafness and Other Communication Disorders (NIDCD) awarded a $410,534 Project Grant to The Medical University of South Carolina (MUSC) under the Research Related to Deafness and Communication Disorders program (CFDA 93.173). The grant, awarded on September 10, 2025, seeks to identify genetic modifiers that influence the penetrance of hearing impairment in the context of Endothelin receptor EDNRB deficiency. The research aims to address the role of the KCNJ16 gene, which...
- This Cooperative Agreement award of $299,430.00 from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the federal grant program "Research Related to Deafness and Communication Disorders" (CFDA 93.173), aims to build scientific capacity to accelerate the uptake of Dissemination and Implementation (D&I) research across NIDCD's mission areas, including hearing, balance, taste, smell, voice, speech, and language. The "Dissemination and...
- This federal Project Grant award for $486,750.00 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the Research Related to Deafness and Communication Disorders (CFDA 93.173) program. The grant supports research to explore the morphological changes and cell polarity mechanisms in supporting cells of the inner ear, which play a critical role in auditory function. The primary awardee, the Jackson Laboratory, a nonprofit biomedical research...
- This Project Grant award of $637,500.00 was provided by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173). The goal of the project is to understand the forward transduction that drives inner and outer hair cell stereocilia, as well as the reverse transduction that amplifies motion in the human cochlea, using a novel finite element modeling technique. The research will focus...
- The University of Pittsburgh received a $610,725 Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD) under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173) effective May 2, 2025 with a completion date of April 30, 2030. The project will characterize the physiological mechanisms contributing to "suprathreshold deficits" in sensorineural hearing loss, where individuals struggle to understand...
- The National Institute on Deafness and Other Communication Disorders (NIDCD), under the CFDA program "Research Related to Deafness and Communication Disorders", awarded a $193,750.00 Project Grant to The Johns Hopkins University. The grant, effective April 1, 2025 through March 31, 2028, will fund research to investigate the neural dynamics and underlying mechanisms in the auditory cortex during implicit learning of complex sounds. The research aims to map the neural circuits...
- This $115,158 Project Grant, awarded on February 1, 2025 by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports research into the neurological mechanisms underlying hearing loss. The central hypothesis is that the presentation of phosphatidylserine acts as a signal to mark inactive spiral ganglion neuron connections with outer hair cells for removal, facilitating...
This Cooperative Agreement award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders program (CFDA 93.173), will support the Hearing Loss Clinical Domain Working Group (HL-CDWG) to curate gene-disease relationships and variant classifications for hearing loss. The $342,002 award, active from Aug 1, 2025 to Jul 31, 2028, will enable the HL-CDWG, an international multidisciplinary team, to thoroughly curate evidence supporting gene-disease relationships and develop standardized, evidence-based variant classification guidelines for hearing loss genes. This work aims to enhance diagnostic accuracy and clinical care for individuals with hearing loss, given the complex genetic and phenotypic heterogeneity of this condition.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $342.0k | 7/29/25 |