Pathogen data network
Active Cooperative Agreement Awarded Last action
- Award ID
- U24AI183840
- Recipient
-
Sib Institut Suisse De Bioinformatique UEI VN2JMQ8KJA43
- Awarding agency
-
National Institute of Allergy and Infectious Diseases
National Institutes of Health, Department of Health and Human Services
- Obligated
- $17,404,062
Award facts
- Assistance listing
- 93.855 Allergy and Infectious Diseases Research
- Completion date 56% complete
- Place of performance
- Switzerland
Award details come from USAspending.gov.
Description
- Abstract
- The pathogen data network (PDN) will nucleate global networks around the mobilization of diverse biodata types, including host and pathogen genomics, transcriptomics, proteins, pathways and networks, imaging and cohorts. The integration and linkage of these data for the purposes of research and public health response will be made possible through the development of a technical framework including specifications, standards, interfaces and reference software implementations. All the publicly available data to be integrated with further datasets and tools from a range of pathogen-related data resources will be made accessible and RE-usable under the pathogens portal (PP), hosted at embl-EBI, and within distributed local pathogen portals (LPP), hosted globally and enabling additional functionalities to be customized for the specific local context. To foster data mobilization, PDN will establish a network of fair local data hubs (LDH) based on reference software implementations to be deployed on locally controlled cloud infrastructure, ideally in countries having signed the nagoya protocol. To achieve trustworthy and equitable sharing of the mobilized data to international repositories, legally compliant with local regulations as well as aligned to international policy, we will also address in-depth issues of trust and ownership and work to provide data-sharing policy options for international and national organizations, ensuring alignment of the PDN project with international policy and its wide adoption by end users. This will include LDH focusing on low and middle income countries. In parallel, we will establish a LDH managers' community of practice to exchange knowledge and expertise, with a focus on capacity building, harmonization and preparedness. Data hubs (DH) hosted centrally will continue existing in parallel, supporting those who lack capacity, resource or expertise to deploy and maintain a LDH. LDH would be able to host personal sensitive data that may not be openly shared but can be made discoverable and accessible for research and public health under proper legal and ethical frameworks. The pathogen analysis system (PAS) will be extended with additional workflows from selected use cases spanning global sewage data, foodborne viruses and linked clinical-epidemiological data. PDN will enable its users to run analyses centrally for DH, and locally or remotely for ldhs. An extensive and global support, outreach and training program will fuel the adoption of the network concept, the connection of infrastructure to its interfaces, and the use of open pathogen data by the global scientific community - both for research and for decision-making. In summary, PDN will develop the networks and all the underpinning components at the technical-, analytical-, trust-, policy-, training- and outreach-levels to truly enable data mobilization and sharing, and the subsequent data integration and linking into a global knowledgebase network serving research needs thanks to open access to data, and public health needs, including preparedness and response, thanks to timely access to controlled-access data and a dedicated surveillance and outbreak dashboard.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $797,562 | |
| Amendment | $2,767,750 | |
| Amendment | $2,767,750 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $2,767,750 | |
| Amendment | $2,767,750 | |
| Amendment | $2,767,750 | |
| Original award | $2,767,750 |
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Quick answers
Who received award U24AI183840?
U24AI183840 was awarded to Sib Institut Suisse De Bioinformatique by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on September 1, 2024.
How much is award U24AI183840 worth?
$17,404,062 has been obligated on U24AI183840.
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