Cooperative Agreement U01FD008425
Award Date
9/1/24
Completion Date
8/31/25
Dollars Obligated
$245K
Funding Federal Agency
Center for Drug Evaluation and Research
Awarding Federal Agency
FDA Office of Acquisition and Grant Services
Awardee
Perspectum, Inc. (N9MKJG4DMFB5)
Federal Grant Program
93.103
Assistance Type
Cooperative Agreement
Place of Performance
South San Francisco, CA 94080, USA
Similar Awards
This federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) provides $1,123,570.00 to Virginia Commonwealth University from September 1, 2024 to July 31, 2028 to conduct research on the role of circular RNAs in cholestatic liver diseases, particularly primary sclerosing cholangitis (PSC). The research aims to examine how H19-induced upregulation of specific circular RNAs,...
This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) totaling $1,384,487 will support research to explore the role of the hepatic lymphatic system in cholestatic liver diseases such as primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC). The study aims to determine whether increasing lymphangiogenesis and lymphatic drainage could be a new therapeutic...
This Cooperative Agreement award from the Food and Drug Administration (FDA) Research program (CFDA 93.103) provides $249,826 in funding to The Critical Path Institute (C-Path) to complete psychometric analyses and develop a quantitative study report to support the qualification of the Chronic Heart Failure Symptom Scale (CHF-SS) as a fit-for-purpose clinical outcome assessment for regulatory decision-making in heart failure drug development. The project involves three main aims: 1) finalizing...
This $499,774 cooperative agreement from the Department of Health and Human Services' Food and Drug Administration will support the University of California, San Diego in qualifying composite quantitative imaging biomarkers for diagnostic enrichment in nonalcoholic steatohepatitis (NASH) clinical trials. Over the one-year period from September 1, 2022 to August 31, 2023, UC San Diego will prepare and submit a biomarker qualification plan to the FDA's Center for Drug Evaluation and Research...
This $806,192 Project Grant awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research supports research to understand the roles of the ATP-binding cassette protein MRP9 in cholangiocyte (bile duct cell) metabolism and its impact on cholangiopathies, which are chronic liver disorders affecting the bile ducts. The research aims to elucidate the molecular and cellular mechanisms by which...
This $1.5 million cooperative agreement from the Department of Health and Human Services' Food and Drug Administration (FDA) Research program (CFDA 93.103) supports the development and validation of a best practices framework for physiologically-based pharmacokinetic (PBPK) analysis to support model-informed biowaivers of fed bioequivalence studies for Biopharmaceutics Classification System Class II drugs. The University of Florida is the primary awardee. Under the award, the University of...
This Cooperative Agreement award from the Food and Drug Administration (FDA) under the FDA Research program (CFDA 93.103) provides $1,489,181 in funding to Duke University, with a sub-award to Sloan-Kettering Institute for Cancer Research, to conduct research on malignant phyllodes tumors (MPT), a rare and aggressive form of breast cancer. The key objectives of the project are to: 1) define the genomic alterations in borderline phyllodes tumors and MPTs, and evaluate associations with clinical...
This $1,999,999 Cooperative Agreement awarded by the Center for Drug Evaluation and Research (CDER), part of the U.S. Food and Drug Administration (CFDA 93.103 Food and Drug Administration Research), will support the development, dissemination, and evaluation of an evidence-based clinical practice guideline for managing perioperative pain associated with abdominal laparoscopic surgeries. The project, titled "Managing Perioperative Pain with Abdominal Laparoscopic Surgery: A Collaborative to...
This Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), provides $309,974 to support the development of a novel, low-cost device called LIVERscope. The LIVERscope device uses advanced magnetic resonance (MR) technology to noninvasively estimate quantitative biomarkers of nonalcoholic fatty liver disease (NAFLD), including liver...
This $604,115 federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) will support a longitudinal observational study by The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to develop non-invasive advanced imaging technologies to predict the development of progressive pulmonary fibrosis in individuals with non-idiopathic pulmonary fibrosis interstitial lung...