Cooperative Agreement U01DE034196

Award Date 9/20/24
Completion Date 6/30/28
Dollars Obligated $695K
Funding Federal Agency
Office of the Director
Federal Grant Program
93.310
Assistance Type
Cooperative Agreement
Place of Performance
Berkeley, CA 94720, USA
Similar Awards
This Cooperative Agreement award of $576,681 from the National Institutes of Health's Trans-NIH Research Support program (CFDA 93.310) to Battelle Memorial Institute's Pacific Northwest National Laboratory supports the development of computational tools to characterize the diverse and poorly understood viral elements that impact the human microbiome. The key objectives are to: 1) develop enhanced methods for detecting viral sequences using graph assemblies, 2) build a sequence- and...
This federal Cooperative Agreement award, titled "The Human DNA Virome: From Petabase Scale to Single-Cell Resolution", is funded by the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310). The $1,061,833 award, made on September 20, 2024, supports research to develop computational and experimental methods to characterize the human DNA virome at unprecedented scale and resolution. Key objectives include: 1) leveraging...
This Cooperative Agreement award, titled "Establishing Laboratory Methods for Quantitative Recovery of Diverse DNA and RNA Viral Sequences from Human Biosamples," is funded by the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310). The primary goals are to: Optimize laboratory methods for recovering and quantifying RNA and DNA viruses from human stool samples, addressing interests in viral isolation, detection,...
This Cooperative Agreement award from the National Institutes of Health (NIH) Office of the Director under CFDA 93.310 Trans-NIH Research Support program will provide $4,000,000 over 5 years starting February 1, 2025 to The Broad Institute, Inc. to establish a Virome Characterization Center (VCC). The VCC will leverage genomics, transcriptomics, imaging, and computational approaches to systematically map and characterize the diversity of viruses present in humans across a cohort of 4,000...
This Cooperative Agreement award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) provides $4,399,999 to The Leland Stanford Junior University to comprehensively identify and characterize the human-associated virome. The project, titled "VAST CENTER: VIROMES ACROSS SPACE(S) AND TIME", aims to advance the understanding of the human virome by accessing unique longitudinal sample cohorts, employing innovative virome profiling methods,...
This Cooperative Agreement award, provided by the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310), will fund a project titled "Whole Body Deep Tissue Characterization of the Human Virome". The $2,255,898 award to the Regents of the University of California, San Francisco (UCSF) will support a 5-year study to investigate the heterogenous distribution and persistence of the human virome across various anatomical regions, histological...
The University of Maryland, Baltimore received a $3,000,337 Cooperative Agreement award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) to establish a Consortium Facilitation, Coordination, and Data Management Center for the Human Virome Project (HVP). The HVP is an ambitious initiative to characterize the communities of bacteriophage and eukaryotic viruses associated with the human body, known as the virome. The Center will leverage expertise and...
The University of Pennsylvania received a $4,000,000 Cooperative Agreement award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310). The goal of this 5-year project, titled "The Oro-Respiratory-Gut Virome Axis Over Space and Time", is to comprehensively characterize the human virome, including viruses of humans, bacteria, and human eukaryotic commensals, across key body sites such as the oral/dental, gut, respiratory tract, and...
The Vanderbilt-Coordinated Human Virome Collaborative Center (V2C2) was awarded a $3,984,525 Cooperative Agreement from the National Institutes of Health's Trans-NIH Research Support program (CFDA 93.310) with a project period from February 1, 2025 to January 31, 2030. The purpose of the V2C2 is to provide a comprehensive, annotated, host-contextualized virome by studying viral presence and interactions with host biology and flora in over 2,450 Hispanic/Latinx individuals and children. Key...
This $459,999 federal Project Grant award from the National Institutes of Health (NIH) Office of the Director (CFDA 93.310 - Trans-NIH Research Support) supports research by the Scripps Research Institute in La Jolla, CA to develop predictive modeling of viral RNA cellular behavior. The key objectives are to: 1) Develop high-throughput technologies that integrate 3D structural ensembles of biomolecules with quantitative measurements of in vitro and cellular functions to build predictive models...

This $695,169 Cooperative Agreement award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) aims to establish tools, databases, and integrated pipelines to enable researchers to thoroughly investigate the impact of viruses in the human virome.

Specifically, the project will develop new genome comparison and clustering approaches to provide a comprehensive genome-based viral taxonomy database, expand host prediction tools by integrating large-scale CRISPR detection and viral phenotype prediction, and establish a new functional annotation pipeline leveraging protein structure prediction and genomic neighborhood analysis. These advanced analytics capabilities will enable researchers to classify newly discovered viruses, link them to their host(s), and identify the genetic potential and potential roles/impacts of these viruses. The award was made to the Lawrence Berkeley National Laboratory, a federally funded research and development center operated by the University of California, and the project will run from September 2024 through June 2028.

Generated 7/1/25, 3:08 AM