This federal Cooperative Agreement award from the National Cancer Institute (CFDA 93.396 - Cancer Biology Research) provides $645,012 to the University of North Carolina at Chapel Hill (UNC-CH) to study how the Epstein-Barr virus (EBV) upregulates the FAM72A gene, which contributes to the development of EBV-driven non-Hodgkin lymphoma (NHL) subtypes. The 5-year project, running from Sep 2024 to Aug 2029, will address the mechanisms by which EBV's upregulation of FAM72A leads to the formation of EBV-positive NHL, including post-transplant lymphoproliferative disease, diffuse large B-cell lymphomas, T-cell lymphomas, NK/T-cell lymphoma, and Burkitt's lymphoma. The funding supports research to advance the understanding of EBV's role in lymphomagenesis, which could inform the development of better prevention, detection, and treatment approaches for these EBV-associated malignancies.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $645.0k | 9/10/24 |