Project Grant R44CA189522

This federal Project Grant award from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the "Discovery and Applied Research for Technological Innovations to Improve Human Health" program (CFDA 93.286), provides $249,000 to Case Western Reserve University to develop an ultrafast photoacoustic histology platform for real-time intraoperative diagnosis. The project aims to create a structured illumination ultraviolet photoacoustic microscopy system capable of...

This three-year, $2.97 million Project Grant from the National Institutes of Health's Trans-NIH Research Support program will support the development of a novel lung research platform to probe pulmonary (patho)physiology in real-time at the cellular level. Trustees of Boston University will receive funding to create the LungEx platform, which includes long-term ex vivo maintenance of mouse and human lungs under near-physiological conditions. A key innovation is a "Crystal" ribcage that...

This $400,000 Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) to the University of Colorado aims to develop a new 3D label-free imaging technology called 3D Dynamic Contrast Optical Coherence Tomography (3D DYC-OCT). This advanced optical imaging system will enable high-speed, high-resolution 3D visualization of ciliary beating dynamics in human airway organoids, providing critical insights into airway cell function relevant to studying lung...

The National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded The Johns Hopkins University a $395,566 Project Grant under the Engineering (47.041) federal grant program. The grant funds research to develop new optical and computational tools to improve histological imaging of unprocessed tissues without the need for tissue slides. Specifically, the grantee aims to create a novel macroscope projecting ultraviolet illumination at high spatial...

This Project Grant award of $1,683,996 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), will support the development of a novel 3D Dynamic Contrast Optical Coherence Microscopy (3D DYC-OCM) technology. The key products and services to be delivered include: Developing a novel swept source architecture and scalable parallel imaging platform to enable 3D...

The National Institutes of Health (NIH) awarded a $749,854 Project Grant under the Research Infrastructure Programs (CFDA 93.351) to Albany Medical College to acquire an Olympus FVMPE-RS multiphoton microscope for intravital microscopy research. This specialized microscope will enable NIH-supported investigators at Albany Medical College and other nearby research institutions to conduct detailed mechanistic studies using mouse models of disease, covering a range of research areas including...

This $400,000 Project Grant award, provided by the National Science Foundation's (NSF) Engineering program (CFDA 47.041), aims to develop a new label-free 3D imaging technology to study ciliary beating dynamics in human airway organoids. The technology, called 3D Dynamic Contrast Optical Coherence Tomography (3D DYC-OCT), will overcome limitations of current imaging methods by providing high-speed, high-resolution 3D visualization of cilia movement without the need for fluorescent labeling. This...

The University of Michigan was awarded a $1.8 million project grant from the National Institutes of Health Office of the Director under the Research Infrastructure Programs federal grant program to purchase a Leica SP8 confocal microscope. The microscope will support over 30 investigators at the University engaged in diabetes, vision, and retinal research by replacing two aging microscopes in the university's shared imaging facility. The new microscope will provide high-speed resonant scanning...

The National Institute of Biomedical Imaging and Bioengineering (NIBIB) awarded a $553,076 Project Grant under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) to the University of Washington. The grant's objective is to develop an advanced computational super-resolution model to enhance the throughput and resolution of chemical imaging techniques, such as stimulated Raman scattering (SRS) microscopy. This research aims to improve...

This federal Project Grant award from the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) provides $942,983 to acquire a Bruker Luxendo TruLive3D light-sheet microscope system. The award, effective September 1, 2024 through August 31, 2025, will enable rapid 3D volumetric imaging of live specimens such as mouse, fly, and zebrafish embryos with high resolution and minimal phototoxicity. This advanced microscope system will benefit a user group of...