Cooperative Agreement R43CA232905

The federal Project Grant award R34AT012767, provided by the National Center for Complementary and Integrative Health (NCCIH) under the Research and Training in Complementary and Integrative Health program (CFDA 93.213), will fund feasibility and acceptability testing of an integrated intervention combining digital cognitive behavioral therapy for insomnia (dCBT-I) and passive body heating (PBH) for the treatment of insomnia disorder. The $737,480 award will support two studies: (1) an iterative...

The U.S. National Institute on Aging (NIA) awarded a $134,000 project grant under the Aging Research program (CFDA 93.866) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), to conduct a pilot study on a digital cognitive behavioral therapy for insomnia (DCBT-I) intervention for older adults undergoing orthopedic surgery. The goal is to evaluate the feasibility and efficacy of this abbreviated DCBT-I protocol in improving sleep and cognitive resilience...

This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will fund a mechanistic clinical trial to evaluate the role of the metabotropic glutamate receptor subtype 5 (mGluR5) in the antidepressant mechanism of cognitive behavioral therapy for insomnia (CBT-I) in adults with major depressive disorder. The $808,417 award, effective May 1, 2025 through March 31, 2030, will be provided to the Research Foundation...

This Project Grant award from the National Center for Complementary and Integrative Health (NCCIH), under the federal Research and Training in Complementary and Integrative Health (CFDA 93.213) program, will fund research to investigate an adaptive intervention to improve pain outcomes following cognitive behavioral therapy for insomnia in patients with comorbid chronic low back pain and insomnia. The total funding amount is $817,330.00, with the project period running from May 15, 2025 to April...

This NCI Early K99/R00 Project Grant award (CFDA 93.398 Cancer Research Manpower) provides $224,968 to Wake Forest University Health Sciences to refine and test a cognitive behavioral therapy for insomnia (CBT-I) intervention for lung cancer survivors. The goal is to enhance the feasibility, acceptability, and impact of CBT-I on insomnia and co-occurring symptoms like fatigue, pain, anxiety, depression, and respiratory issues. The award supports stakeholder engagement to refine the CBT-I...

This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants (CFDA 93.242) program, will fund a study on the efficacy of light therapy for reducing symptoms of obsessive-compulsive disorder (OCD) in adults with delayed sleep-wake patterns. The $393,212 award will be used to compare the effects of light therapy (n=20) versus placebo light therapy (n=20) on OCD symptoms and circadian rhythms in adults with OCD and delayed bedtimes....

The National Institutes of Health National Center for Complementary and Integrative Health awarded New York University $785,637 under the Research and Training in Complementary and Integrative Health program (CFDA 93.213) from June 2021 through May 2025. This Cooperative Agreement will support the development and pilot testing of telephone-delivered and video-based Mindfulness-Based Cognitive Therapy (MBCT) protocols for patients with migraine headaches and depressive symptoms. Specifically, the...

This federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will fund a $121,424 study examining the relationship between early sleep disruption, functional brain networks, and developmental trajectories in infancy. The study will leverage data from two longitudinal NIH-funded projects - the Infant Brain Imaging Study (IBIS) and the Healthy Brain and Child Development (HBCD) Study - to (1) investigate how...

This $736,503 Project Grant award from the National Institute on Aging's Aging Research program (CFDA 93.866) will fund a clinical trial to evaluate the effects of combining cognitive-behavioral therapy for insomnia (CBTI) and morning bright light treatment (MBLT) on chronic post-surgical pain (CPSP) and opioid use in older adults undergoing total knee arthroplasty surgery. The study aims to determine if this multimodal sleep-focused intervention can reduce the incidence of CPSP and opioid...

The National Science Foundation (NSF) Directorate for Engineering awarded the University of Pittsburgh a 3-year, $350,000 Project Grant to develop an innovative closed-loop brain-computer interface (BCI) system for use in exposure therapy for socially fearful teenagers with depression and anxiety. The proposed technology synchronizes electroencephalogram (EEG) monitoring with augmented reality (AR) simulations of social fear scenarios, enabling real-time detection of fearful responses and...