Cooperative Agreement R43CA189522

The University of Michigan was awarded a $1.8 million project grant from the National Institutes of Health Office of the Director under the Research Infrastructure Programs federal grant program to purchase a Leica SP8 confocal microscope. The microscope will support over 30 investigators at the University engaged in diabetes, vision, and retinal research by replacing two aging microscopes in the university's shared imaging facility. The new microscope will provide high-speed resonant scanning...

The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $300,000 EAGER (Early-Concept Grants for Exploratory Research) project grant to The Research Foundation for The State University of New York (RF SUNY) to establish near-ultraviolet (NUV) coherent anti-Stokes Raman scattering (CARS) microscopy for highly sensitive imaging of native biomolecules. This technology will be applied to develop label-free digital pathology for brain...

This $255,991 National Science Foundation project grant supports the development of an automated system for rapid analysis of biopsy samples by Amcyt, Inc. The system aims to increase the efficiency and accessibility of fine needle aspiration biopsy procedures through three automated processes: sample smearing, staining, and image capture. This addresses a critical need to improve biopsy analytics and potentially eliminate up to 20% of failed procedures due to sampling errors. By automating...

The University of Maryland, Baltimore was awarded a $1,799,728.98 Project Grant from the Department of Health and Human Services National Institutes of Health Office of the Director to purchase a state-of-the-art light sheet fluorescence microscope. The microscope will be situated in the university's established Confocal Core Facility, which will oversee use, training, and service of the instrument for nine NIH-funded research teams. Light sheet fluorescence microscopy is well-suited for...

This National Science Foundation Project Grant of $495,000 will support the development of biopsy-free, label-free three-dimensional virtual histology of intact skin through March 2025. Funded under the Engineering program (CFDA 47.041), the award to the University of California, Los Angeles aims to advance a machine learning-based technique to transform 3D skin images into virtually stained images that can facilitate accurate and rapid diagnosis of skin lesions without biopsy. Specifically, the...

This $750,000 Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) will fund the acquisition of a Leica Stellaris 8 DIVE multiphoton microscope system for the UC San Diego School of Medicine Microscopy Core. The new multiphoton microscope will replace the previous inoperable system and provide cutting-edge imaging capabilities to support a broad range of NIH-funded biomedical research projects across the university. The...

This $450,173 federal Project Grant award from the National Institutes of Health (NIH) Office of Research Infrastructure Programs (CFDA 93.351) will provide a new light-sheet microscopy system to the Seattle Children's Research Institute (SCRI), University of Washington (UW), and other partner institutions in the Seattle area. The goal is to enable biomedical researchers to image tissue structure from whole organism scale to microscopic resolution, supporting a diversity of basic and...

Visikol Inc. received a $4,103,265 Project Grant award from the National Cancer Institute, a division of the Department of Health and Human Services, under the Cancer Detection and Diagnosis Research program (CFDA 93.394). The award will support the development of a 3D imaging diagnostic tool to improve characterization of metastatic melanoma in sentinel lymph node biopsies. Visikol will conduct a retrospective clinical study using archived negative sentinel lymph node biopsy tissue blocks to...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Small Business Innovation Research (SBIR) Phase I project award of $274,998 to Magnify Biosciences Inc. aims to develop an automated "AutoMagnify" device that physically expands biological specimens up to 1,000 times in 3D while preserving spatial and molecular integrity. This advancement will enable conventional light microscopes to achieve nanoscale imaging resolution capabilities...

Federal Grant Award Summary Massachusetts General Hospital received a $1.52 million Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), awarded September 1, 2025, with a completion date of June 30, 2029. The award supports the development and validation of mechanomicroscopy, an innovative endoscopic imaging platform designed to enable transbronchial assessment of pulmonary hypertension (PH) due to lung disease...