Cooperative Agreement DEFC3608GO18080

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $274,918 to Cascade Biocatalysts Inc. will fund research and development to demonstrate the commercial feasibility and scalability of a patent-pending approach for stabilizing enzymes through engineered polymer-enzyme interactions. The goal is to enable environmentally sustainable, low-carbon chemical manufacturing processes that utilize enzymes as catalysts, which can decrease...

Lanzatech, Inc. was awarded a $3.71 million cooperative agreement from the Department of Energy's Advanced Research Projects Agency - Energy (ARPA-E) to develop a carbon-negative chemical production platform. Under the three-year award beginning October 2021, Lanzatech will engineer a non-traditional host strain to maximize stable ethanol production from high hydrogen-to-carbon monoxide gas uptake ratios, enabling a single-step, direct carbon dioxide gas fermentation process integrated with...

This $275,000 Project Grant award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships program) to Encore CO2 LLC supports the development of scalable technology to convert CO2 into high-value products, starting with ethanol production. The project aims to advance sustainable manufacturing by using renewable energy to transform CO2 and water into common products like ethanol, which can be used in beverages, sanitizers, and consumer goods. The...

This two-year, $200,000 Project Grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems will fund research at the Long Beach Research Foundation to develop multi-activity proteins for improved carbohydrate deconstruction. Specifically, the Foundation will produce and test 85 engineered multi-activity proteins containing two catalytic domains each. These proteins aim to increase biomass conversion for alternative fuels and...

This Project Grant from the United States Department of Agriculture's National Institute of Food and Agriculture, under the Small Business Innovation Research (SBIR) Program / Small Business Technology Transfer (STTR) Program (CFDA 10.212), provides $175,000 to PCC Hydrogen Inc. to investigate using ethanol as a feedstock for distributed hydrogen production. Ethanol is a less hazardous carrier of hydrogen than other hydrocarbons and can be produced from various biomass sources. This project will...

This Project Grant award from the U.S. Department of Agriculture National Institute of Food and Agriculture under the Small Business Innovation Research (SBIR) / Small Business Technology Transfer (STTR) Program (CFDA 10.212) supports the development of a novel bioprocess to produce n-butanol, an industrial solvent and advanced biofuel, from low-cost agricultural residues such as corn stalk. The $175,000 award to Bio-Missions LLC, a for-profit, veteran-owned limited liability company, aims to...

Via Biofuels Inc. received a $175,000 Phase I award from the National Institute of Food and Agriculture (NIFA) under the Small Business Innovation Research (SBIR) Program (CFDA 10.212) to develop a genetically engineered yeast strain capable of converting whey permeate—a lactose-rich waste byproduct from dairy processing—into 3-methylanisole (3-MA), a versatile chemical compound with applications as a gasoline replacement, plastic precursor, and sustainable aviation fuel feedstock. The...

The Department of Energy Office of Science awarded Innosense Corporation a $1.92 million project grant under the Office of Science Financial Assistance Program (CFDA 81.049) to support the development of efficient and cost-effective enzymatic conversion of lignocellulose feedstock to useful bioproducts. The three-year award, issued on February 22, 2021 with a completion date of April 3, 2024, will fund Innosense's work breaking down lignocellulose into bioproducts using novel enzyme...

This National Science Foundation (NSF) Engineering program (CFDA 47.041) award of $150,000 to The Trustees of Columbia University in the City of New York provides funding for a collaborative research project to investigate using hydrogen peroxide, a cellular waste product, as an alternative energy source for efficient biofuel and biochemical production. The key objectives of the project are to: 1) develop an E. coli strain platform to control and monitor hydrogen peroxide production, 2) create...

Integrated Dynamics, Inc. received a $245,300 Small Business Innovation Research (SBIR) Phase I project grant from the National Science Foundation (NSF) Technology, Innovation, and Partnerships program (CFDA 47.084), awarded October 1, 2025, with completion targeted for June 30, 2026. The company will conduct research and feasibility analysis to engineer a hyperthermophilic microorganism strain capable of producing volatile organic compounds (VOCs), specifically ethanol and acetone, through...