Cooperative Agreement 58126580590

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $769,201 Project Grant (CFDA 93.855 - Allergy and Infectious Diseases Research) to the University of Massachusetts Medical School (UMass Medical) to discover optimal combinations of Bacillus thuringiensis (Bt) crystal proteins and small molecule anthelmintic drugs to suppress drug resistance and improve efficacy against parasitic gastrointestinal nematodes that infect approximately 1.5 billion people globally. The...

This federal Project Grant award, valued at $226,738.00 and provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), is intended to support research aimed at enhancing the efficacy of the anthelmintic drug emodepside for treating filarial nematode infections. The key objectives of this two-year project are to: 1) characterize the pharmacology of the endogenous SLO-1/2 potassium channels in...

This $198,770 Cooperative Agreement award from the U.S. Food and Drug Administration's (FDA) Center for Veterinary Medicine (CVM) under the FDA Research program (CFDA 93.103) will support the expansion of an ongoing, nationally representative system for collecting on-farm antimicrobial use (AMU) data in the U.S. poultry industry. The project, led by Mindwalk Consulting Group LLC, will build upon an existing public-private partnership that currently collects AMU data covering approximately 85% of...

This Cooperative Agreement award from the Food and Drug Administration (FDA) under the FDA Research program (CFDA 93.103) provides funding of $162,501 to The Trustees of the University of Pennsylvania for a pilot study on veterinary antifungal use and resistance. The primary goals are to: Develop and implement a survey to assess veterinarians' knowledge, attitudes, and practices related to antifungal resistance, risk factors, diagnosis, and prescribing in companion animal medicine. Collect...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $364,324 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The Johns Hopkins University to conduct research on the mechanisms of resistance to the anthelmintic drug emodepside. The grant aims to identify genetic variations and biotransformation pathways that contribute to emodepside resistance in the parasitic nematode Caenorhabditis elegans, with the goal of developing...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $155,686 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Baylor College of Medicine. The two-year grant, effective February 1, 2025 through January 31, 2027, will fund a prospective study to identify an optimal screening strategy for Strongyloides infection in at-risk U.S. populations, and evaluate diagnostic tests as a "test-of-cure" for this parasitic disease. The...

This Project Grant award of $792,845 from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports research to georeference, curate, and augment the largest global host-helminth (parasitic worm) database. The researchers at the University of South Carolina will clean and enhance this database, which currently contains over 250,000 interactions between helminth parasites and their hosts, to improve its accuracy and accessibility for researchers studying...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $810,158 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to The University of Texas Health Science Center at San Antonio. The goal of this research is to develop a novel antischistosomal compound that can be used in combination with the current treatment, praziquantel, to improve efficacy and mitigate resistance against all three major human Schistosoma species. The project involves...

This Cooperative Agreement award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $702,204 to the London School of Hygiene and Tropical Medicine (LSHTM) to conduct research on complex malaria in India. The key products and services to be delivered include: A four-year community-based cohort study in three districts of Odisha, India to investigate factors supporting persistent malaria...

This $418,010 Cooperative Agreement award from the United States Department of Agriculture's Animal and Plant Health Inspection Service (APHIS) under the Plant and Animal Disease, Pest Control, and Animal Care Federal Grant Program (CFDA 10.025) will enable the National Association of State Departments of Agriculture (NASDA) to utilize and expand the AMR analytics, predictive modeling, and forecasting tools developed in the prior year. The primary purpose is to enhance understanding of...