Cooperative Agreement 2607522
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded $763,328 to the Research Foundation of the City University of New York (doing business as the Advanced Science Research Center) on June 15, 2026, under the Biological Sciences program (CFDA 47.074) to develop artificial intelligence-driven methodologies for designing dynamic protein structures. The project will test whether existing designed proteins exhibit different conformational dynamics than natural...
- This $500,000 federal Project Grant awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049) supports research at Northwestern University to develop de novo designed proteins as mechano-responsive junctions in protein-polymer networks. The key objectives are to: (i) synthesize and computationally simulate de novo designed proteins and their respective protein-polymer networks, and (ii) develop techniques for mechanical characterization...
- The National Science Foundation awarded Northwestern University a $525,000 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to develop protein crystallization programmed with DNA. This three-year award beginning June 1, 2021 will support research to promote progress in the mathematical and physical sciences by increasing understanding of major problems through the development of new techniques to crystallize proteins using DNA programming. The University will...
- This $1,500,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program will support research at Northwestern University to develop innovative protein-based biomaterials. The research aims to (1) engineer mussel foot proteins with superior underwater adhesive properties compared to wild-type sequences, and (2) create resilin-inspired bioelastomers with high strength while retaining natural mechanical resilience. The proposed...
- The National Science Foundation Division of Materials Research awarded Colorado State University $360,004 on July 1, 2026, under the Mathematical and Physical Sciences program (CFDA 47.049) to develop machine learning protocols for designing protein-DNA co-crystal materials that function as three-dimensional scaffolds for capturing and determining the atomic-level structures of biological molecules via X-ray crystallography. The award supports research aimed at accelerating structure...
- The National Science Foundation Division of Biological Infrastructure awarded North Carolina State University $1,013,194 on August 15, 2026, to develop software that predicts protein binding to DNA and RNA by combining artificial intelligence tools with biophysical principles. Work performance occurs in Raleigh, North Carolina, with a completion date of July 31, 2029. The project integrates sequence, structure, and dynamics data to advance understanding of protein-nucleic acid interactions...
- The National Science Foundation awarded the Research Foundation of the City University of New York $4,667,934 under a Cooperative Agreement on August 1, 2026, to establish and operate AI-BIOME, a cloud-programmable national laboratory for AI agent-driven discovery, design, and production of advanced biomaterials through autonomous experimentation, robotics, and artificial intelligence. AI-BIOME will integrate AI agents, robotic cloud laboratories, and advanced characterization within a shared...
- The National Science Foundation awarded The University of Chicago a $5 million Cooperative Agreement on August 1, 2026, under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to establish POLARIS, a programmable cloud laboratory for AI-guided soft materials discovery. POLARIS will integrate more than twenty automated synthesis, processing, and characterization platforms—including the PolyBot polymer synthesis robot, film processing, device fabrication systems, and...
- The Department of the Army Materiel Command Research Development and Engineering Command awarded a cooperative agreement totaling $105,304 to Northwestern University on April 1, 2026, to develop nanobiomaterials from self-assembling protein scaffolds through protein engineering and bioconjugation. The award supports basic scientific research under CFDA 12.431, which funds fundamental knowledge advancement in chemical, life, physical, engineering, materials, and related sciences to address...
- The National Science Foundation Division of Computing and Communication Foundations awarded the University of Illinois $530,625 on July 1, 2026, under the Computer and Information Science and Engineering program (CFDA 47.070) to develop multimodal generative artificial intelligence models for autonomous biomolecular design and accelerated discovery. The research will create a unified, self-improving AI framework that integrates molecular sequence and three-dimensional structure co-design with...
The National Science Foundation awarded Northwestern University a $4.411 million cooperative agreement on August 1, 2026, to establish the DREAM Cloud Lab for Protein Engineering under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The award funds development of an AI-driven, automated platform that combines artificial intelligence with high-throughput experimental automation to accelerate protein engineering. The DREAM system will implement a design-build-test-learn cycle using cell-free protein synthesis and machine learning, enabling users across the United States to design custom proteins for applications in manufacturing, critical mineral mining, agriculture, advanced materials, and health. The platform will train the next generation of scientists in AI and biology while supporting domestic bioeconomy growth and national competitiveness in biotechnology. Work is performed at Northwestern University's Evanston, Illinois campus. The period of performance runs through July 31, 2030. The award obligates $4.411 million in total funding.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $4.4m | 7/21/26 |