This Cooperative Agreement award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) is funding a project led by the University of California, Irvine (UC Irvine) to develop more efficient methods for cell-free biomanufacturing. The $2,996,108 project, which runs from May 1, 2025 to April 30, 2028, aims to create a robust, reusable platform capable of sustaining multi-enzyme cascades for the efficient synthesis of...
This Project Grant award from the National Science Foundation (NSF) under its Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $275,000 to Tectaria Bio LLC to engineer cell lines with activated proteasomes for increased biomanufacturing efficiency. The project aims to test the feasibility and application of a novel technology to significantly increase the protein production capabilities of cell lines used in the manufacture of biologics, gene therapies, and vaccines....
This $500,000 Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences, under the Biological Sciences federal grant program (CFDA 47.074), will support research to develop an end-to-end continuous manufacturing process for cell therapies using robotics and microfluidic technologies. The Georgia Tech Research Corporation will receive funding to create a more integrated workflow based on microfluidic device-enabled genetic engineering, cell expansion, and...
This Project Grant award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $305,000 to Cellecho, Inc., a minority-owned small business, to develop a microchip-based technology for advanced cell engineering. The project aims to create a platform that leverages acoustic-electric micro-vortices to precisely and efficiently deliver genetic materials like DNA, mRNA, and proteins to cells, enabling complex cell...
This Cooperative Agreement award, funded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), aims to develop a scalable, cost-effective, and cell-free biocatalytic process for producing methylene butyrolactone (MBL), a bio-based acrylate monomer. The $2,233,515 project led by Arzeda Corp will leverage artificial intelligence and advanced protein engineering to redesign natural enzymes and utilize non-natural cofactors to...
Cornell University received a $100,000 Project Grant award from the National Science Foundation's Technology, Innovation, and Partnerships program to develop a cell-free biosensing platform integrating transmembrane proteins. The award period is from July 1, 2022 to December 31, 2022. Specifically, the university will utilize recent advances in biotechnology and bioelectronics to establish a process for rapidly assembling customized transmembrane proteins into a biomimetic sensing device without...
The Georgia Tech Research Corporation was awarded a $1,077,799 project grant from the National Science Foundation Division of Molecular and Cellular Biosciences on September 1, 2021 to complete work by August 31, 2025. The grant falls under the Biological Sciences program (CFDA 47.074), which aims to promote progress in the biological sciences and strengthen the nation's scientific enterprise through increasing knowledge and enhancing understanding of major problems. Specifically, the grant will...
This Cooperative Agreement award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $2,526,095 to Arzeda Corp to develop a new cell-free enzymatic system that can convert carbon dioxide into methanol using electricity as the power source. The key products and services to be delivered include: Designing new enzymes using AI that can be directly powered by electricity rather than chemical energy sources, enabling...
This Cooperative Agreement award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $1,248,994.00 to Opera Bioscience, Inc., a woman-owned small business located in Evanston, Illinois. The project aims to further develop the company's innovative bacterial protein secretion platform technology into a commercially viable, cost-effective protein expression system capable of producing multiple classes of proteins...
This Project Grant award of $275,000 from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) supports the development of a novel platform for massive, empirical, and scalable generation of small molecule and protein interaction data. The goal is to enable more efficient discovery of new medicines using machine learning. The key products and services to be delivered under this SBIR Phase I award include: Demonstrating the ability to identify...