This Cooperative Agreement award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program provides $1,250,000 in funding to Zaiput Flow Technologies LLC, a small business manufacturer based in Waltham, Massachusetts. The project aims to further develop an innovative continuous crystallization device to improve pharmaceutical manufacturing processes. Key goals include demonstrating excellent performance and scalability of the technology...
This $1,000,000 Cooperative Agreement award from the National Science Foundation's (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program aims to accelerate R&D in the pharmaceutical industry through the development of streamlined machine learning algorithms for small data applications in advanced manufacturing. The project, awarded to Sunthetics Inc., seeks to save time and resources by up to 95% in lead optimization and route scouting during pre-clinical drug development by...
The National Science Foundation (NSF) awarded a $951,394 Cooperative Agreement under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Ballydel Technologies Inc. for the development of serialized anti-counterfeit labeling technology for pharmaceutical and biological products. The project aims to create a scalable manufacturing process for imprinting covert, encrypted patterns onto labels for individual vaccine vials, incorporating serialized codes to enable traceability...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Om Therapeutics Inc. will support the development of a system to enable the rapid, scalable, and cost-effective discovery of new medicines using machine learning. The project aims to encapsulate proteins and small molecules in millions of miniaturized compartments to screen for interactions that could identify novel drug candidates. The key innovations include...
This Cooperative Agreement award from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $1,213,322 to Lavo Life Sciences Inc. for the development of a physics-based machine learning platform to predict the crystal structure and solid form properties of new drug molecules. The goal is to accelerate the development and commercialization of new pharmaceutical products by enabling scientists to optimize drug products more...
This National Science Foundation (NSF) Cooperative Agreement under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program provides $1,016,000 in funding to Nostopharma LLC to develop an innovative, sustained-release, and biodegradable drug delivery platform for localized treatment of post-traumatic injuries. The goal is to create a medication delivery system using anti-inflammatory nanoparticles embedded with a Hedgehog pathway antagonist, arsenic trioxide, to address unmet...
This Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program provides $305,000 to Resonantia Diagnostics, Inc. to develop a rapid diagnostic platform for identifying pathogens and determining antimicrobial susceptibility within 60 minutes. The project aims to advance an acoustic sensor-based technology that can accurately detect pathogens at low concentrations and test their susceptibility to a diverse range of...
This Project Grant award of $305,000.00 from the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program supports the development of a rapid point-of-care antimicrobial susceptibility testing (AST) kit. The goal is to create a microfluidic-based platform that can provide actionable AST results within 6-9 hours, compared to the current 3-5 day turnaround, to help physicians prescribe the optimal antibiotic dosage sooner. This will reduce...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award for $275,000 will support the development of a plasmonic nanopore sensor device for quality control of adeno-associated viruses (AAVs) used in gene therapy. The proposed device will enable accurate characterization of AAV payload (single-stranded DNA, double-stranded DNA, or empty) at low, pre-scale-up concentrations to optimize formulations. The project aims to demonstrate the...
This $228,697 National Science Foundation award under the Engineering program (CFDA 47.041) will support the development of an optical biosensor technology to facilitate drug screening and validation efforts. Auctus Biologics, Inc. will utilize a proprietary temperature, pH, and chemically stable protein composed of two fragments that bind with antibody-like affinity and specificity. Over the one-year period ending January 2023, the company will establish the technology's suitability for...