Sbir phase II: a cryo-EM automation and intelligence platform for drug discovery
Ended Cooperative Agreement Awarded Last action
- Award ID
- 2135832
- Recipient
-
Health Technology Innovations, Inc. UEI SKHEZ9ANNR43
- Awarding agency
-
National Science Foundation
- Obligated
- $1,198,642
Award facts
- Assistance listing
- 47.084 NSF Technology, Innovation, and Partnerships
- Completion date
- Originally
- Place of performance
- Portland, OR 97239, USA
Award details come from USAspending.gov.
Description
- Abstract
- The broader impact/commercial potential of this small business innovation research (sbir) phase II project is to improve disease research and drug discovery. Cryogenic electron microscopy (cryo-EM) is one of the most impactful and vital tools of biological structure analysis today. The proposed project improves the current methods to achieve better accuracy and productivity, with faster user training. The proposed project improves imaging by cryo-EM. The images currently generated by cryo-EM are highly noisy and thus requires extensive processing to build recognizable structures (proteins and others). Single-particle cryo-EM is a method that produces images of individual particles and can potentially analyze biological structures at the single-molecule level. This project uses artificial intelligence/machine learning (AI/ML) techniques to mitigate the issues. AI/ML algorithms can automate the workflow, facilitating quality data and the development of 3D models. This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the foundation's intellectual merit and broader impacts review criteria.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $198,686 | |
| Original award | $999,956 |
Quick answers
Who received award 2135832?
2135832 was awarded to Health Technology Innovations, Inc. by National Science Foundation on February 1, 2022.
How much is award 2135832 worth?
$1,198,642 has been obligated on 2135832.
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