Purchase Order AG32SCP170344

The National Institutes of Health National Institute on Drug Abuse awarded a $288,375 firm fixed price purchase order to Curia Global Inc., doing business as Amri, to provide non-GMP synthesis of up to 100 ligands that bind the KIAA0203 protein. Under the terms of the contract, Amri will synthesize the ligands in 2-10 milligram quantities over a one-year period of performance. Amri must dedicate two full-time scientists and one part-time scientist at 25% effort to update progress. There is no...

This firm fixed-price contract for $80,300 was awarded by the Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences to Affinity Research Chemicals Inc. of Stanton, Delaware. The contract calls for the delivery of 5 kilograms of non-GMP grade methyl 4-(((5-phenylpyrazin-2-yl)methyl)carbamoyl)benzoate, a key intermediate and regulatory starting material required for further process development and cGMP manufacture of the...

This is a $40,500 firm fixed-price purchase order awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to Polyorg, Inc., a for-profit manufacturer located in Leominster, MA. The order is for specialized chemical reagents including Fmoc-PNA monomers and Bhoc Nucleobase Acids, which are essential starting materials for NIDDK's research on thyclotides - molecules with potential diagnostic applications. The purchase order was awarded on a sole-source basis under...

This federal contract award was made by the Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences to Synovel Laboratory LLC, a self-certified small disadvantaged business and limited liability company. The contract was for the synthesis of 100 grams of the chemical compound NCGC00413972, with a period of performance from June 23, 2021 to August 22, 2021. The contract was awarded on a firm fixed price basis with a...

This firm-fixed-price purchase order contract was awarded by the National Institute on Drug Abuse (NIDA), a component of the National Institutes of Health (NIH), to Wuxi Apptec (Hongkong) LIMITED. The contract provides for the synthesis and delivery of 0.2 grams of the small molecule Marizomib, with a purity of 95% or above, as well as a report detailing the synthesis and purity information. The contract has a ceiling value of $10,800.00 and a performance period of approximately 20 weeks from...

This firm fixed-price purchase order, valued at $10,900, was awarded by the Department of Health and Human Services' National Institutes of Health National Center for Advancing Translational Sciences to Pointcare Systems Inc. R&D Division, doing business as Chirosolve, for the synthesis of tert-butyl (R)-3-(5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)piperidine-1-carboxylate in a 75 gram quantity with over 95% purity. The solicitation sought synthesis and delivery of the specified intermediate...

This is a $36,000.00 firm fixed-price contract awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which is part of the National Institutes of Health (NIH), a civilian agency. The contract was awarded to Entrechem SL, a for-profit manufacturer located in Spain, to provide 100g each of two specialized chemical compounds, (1S,2S)-trans-N-Boc-Tetrahydro-3,4-furandiamine and (1R,2R)-trans-N-Boc-Tetrahydro-3,4-furandiamine. These compounds are needed as starting...

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $99,000.00 firm-fixed price purchase order to Cyclope Bio SL, a for-profit manufacturer, to acquire Enantiomers of Cyclopentane Diamine and Tetrahydrofuran Diamine. These chemicals are essential starting materials for the NIDDK's Synthetic Bioactive Molecules Section's research on developing new diagnostic kits to detect nucleic acids associated with diseases. The purchase order has a completion date of...

This is a $3,171,368.00 cost-plus-fixed-fee delivery order awarded to Alchem Laboratories Corporation, a for-profit manufacturer of pharmaceutical products, by the National Cancer Institute (NCI), a civilian agency. The contract is for the synthesis of up to ten non-GMP (non-Good Manufacturing Practice) small molecule samples per year, as continuity for the NCI's Program 66C, through September 2026. Alchem Laboratories holds multiple federal indefinite delivery vehicle (IDV) contracts for...

The Department of Health and Human Services Food and Drug Administration (HHS FDA) awarded a $95,010 firm fixed price purchase order to Phoenix NMR LLC of Loveland, Colorado. The contract is to deliver a solid-state, double resonance, X/F-H nuclear magnetic resonance (NMR) probe capable of 40 kHz cross-polarization, magic angle spinning to support research at the FDA's Center for Food Safety and Applied Nutrition. Key requirements as outlined in the solicitation include the probe and components,...