This federal contract was awarded by the Department of Health and Human Services' National Institutes of Health (NIH) and National Institute on Drug Abuse to Xtal Biostructures, Inc., a biotechnology company that specializes in protein crystallization, x-ray crystallography, and biochemical product services. The $12,500.00 firm fixed price purchase order contract is for Xtal Biostructures to provide protein crystallization, x-ray crystallography, testing, and protein generation services to...
This federal contract award, valued at $148,110.00, was issued by the National Cancer Institute (an agency of the National Institutes of Health) to Xtal Biostructures Inc., a biotechnology company that specializes in protein crystallization, x-ray crystallography, and biochemical product generation. The contract is for the "GENERATION OF SITE SPECIFIC PHOSPHO-THREONINE PROTEIN STANDARDS FOR USE IN CANCER ASSAYS". This work supports the National Cancer Institute's research efforts. Xtal...
The National Center for Advancing Translational Sciences (NCATS), a civilian agency within the Department of Health and Human Services, awarded a $247,500 firm-fixed-price purchase order to Schrodinger, Inc. for X-ray crystallography (XRC) structure studies and surface plasmon resonance (SPR) studies. This requirement supports the agency's efforts to optimize compounds against bacterial enzymes. Schrodinger, Inc. is a for-profit organization that has previously received prime federal contracts...
This purchase order contract was awarded by the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health (NIH), to Curia Global Inc. (doing business as Amri) for $79,400. The contract is for X-ray crystallography studies of ALDH1A2 to crystallize two novel small molecules within the enzyme to assist with structure-based drug design as part of an ongoing medicinal chemistry campaign. Specifically, the contractor will perform X-ray crystallography...
This federal contract award was issued by the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health (NIH), to Cayman Chemical Co Inc., a small business manufacturer of biochemical products and research tools. The $132,476.28 firm fixed-price purchase order is for the supply of "Small Molecules for NCATS Pharmacologically Active Chemical Toolbox (NPACT)," which supports NCATS' drug discovery and translational research initiatives. Cayman...
The Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences awarded a $12,472 firm fixed price purchase order to Proteinsimple, a division of Bio-Techne Corporation doing business as Bio-Techne, to provide protein analysis services and equipment. The place of performance is in Potomac, Maryland through October 13, 2023. As part of NIH's efforts to advance translational sciences and support, this award will enable Proteinsimple to...
<p>This firm-fixed-price purchase order contract was awarded by the National Center for Advancing Translational Sciences, a civilian federal agency, to Helix Biostructures LLC, a self-certified small disadvantaged business. The $24,500.00 contract is for crystallization and structure solution services for biliverdin reductase A. The work is to be performed in Potomac, MD and has an ultimate completion date of March 2, 2025. The contract does not have a set-aside designation.</p>
This $29,376 firm-fixed-price purchase order was awarded by the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health (NIH), to Reaction Biology Corporation, a self-certified small disadvantaged business. The award is to obtain kinase hotspot assay compound testing services from Reaction Biology. This contract is not associated with a larger vehicle. The purpose is to test 120 novel small molecule compounds for inhibitory activity...
This is a firm fixed-price purchase order awarded by the Department of Health and Human Services' National Institutes of Health National Center for Advancing Translational Sciences to Activx Biosciences, Inc., a foreign-owned for-profit organization. The $180,600 contract is for kinase profiling services, with a completion date of November 29, 2022. Activx Biosciences has previously provided similar drug discovery and profiling services to other NIH entities such as the National Cancer Institute...
This is a firm fixed price purchase order contract awarded by the Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences to Proteros Biostructures GMBH, a foreign-owned for-profit organization and manufacturer of goods. The contract is for $38,035.00 and is for x-ray structure analyses of eEF1A2 and c-Abl in complex with ligands. The contract was awarded on September 3, 2015 and has a completion date of September 7, 2016....
This federal contract award to Xtal Biostructures Inc., a small business subchapter S corporation, was issued by the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health (NIH). The $97,000 firm-fixed-price purchase order is for protein crystallization and x-ray crystallography services on the Large Tumor Suppressor Kinase 1 (LATS1) protein to support NCATS' preclinical research initiatives. The original sources sought notice was issued as a small business set-aside. Xtal Biostructures is a subsidiary of Schrodinger, Inc., which has also received prior federal contract and grant awards from agencies such as the Department of Justice and NIH for computational drug design solutions and biophysical studies.