Purchase Order 75N91022P00919
Award Date 9/16/22
Potential Completion Date 9/15/23
Potential Value $157K
Federal Agency
Awardee
Ultimate Awardee
Not listed NAICS Category
PSC Category
Federal Contract Vehicle
- Not listed
Set-Aside Type
No Set-Aside Used
Extent Competed
Competed under SAP
Major Defense Program
Not listed Pricing Type
Firm Fixed Price
Place of Performance
Watertown, MA 02472, USA
Solicitation Procedures
Simplified Acquisition
Number Of Offers Received
2
Legislative Mandate
Not listed National Interest Action
Not listed Research Type
Not listed Primary Consortia Member
Not listed Similar Awards
- This is a federal contract awarded by the National Center for Advancing Translational Sciences (NCATS), a civilian agency within the Department of Health and Human Services (HHS), to Cyprotex US LLC, a leading contract research organization specializing in predictive toxicology and ADME (absorption, distribution, metabolism, and excretion) research. The $18,024.00 firm fixed-price purchase order contract is for the testing of two compounds against key ADME and DMPK (drug metabolism and...
- This firm fixed price purchase order awards $56,313 to Cyprotex US LLC to provide in vitro absorption, distribution, metabolism, excretion, and toxicity (ADMET) characterization services in support of the Department of Health and Human Services (HHS), National Institutes of Health (NIH), National Cancer Institute's (NCI) Developmental Therapeutics Program (DTP). The contractor will evaluate two small molecule drug candidates total across 11 specified in vitro ADMET assays, including metabolic...
- This is a firm-fixed-price purchase order contract awarded by the National Center for Advancing Translational Sciences (NCATS), a component of the U.S. Department of Health and Human Services (HHS), to Cyprotex US LLC, a foreign-owned, for-profit contract research organization. The $80,000 contract is for the provision of testing services for 30 compounds, including conducting cytochrome P450 (CYP) inhibition testing, Caco-2 permeability assays, and other absorption, distribution, metabolism,...
- This is a firm fixed price purchase order awarded by the Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) to Cyprotex US LLC, a foreign-owned for-profit organization, for $153,215.00 to conduct testing of compounds in absorption, distribution, metabolism, and excretion (ADME) assays over a 1-year period from March 5, 2021 to March 4, 2022. The contract was awarded sole-source without full and open...
- This is a $24,138.00 firm fixed price purchase order awarded by the Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) to Cyprotex US LLC, a foreign-owned for-profit contract research organization. The contract is for conducting testing of compounds in cytochrome P450 (CYP) inhibition assays. Cyprotex has previously been awarded prime federal contracts by agencies such as the Environmental Protection...
- This is a firm-fixed-price purchase order awarded by the National Institute on Drug Abuse (NIDA), a civilian agency under the Department of Health and Human Services, to Cyprotex US LLC, a foreign-owned for-profit contract research organization. The $109,392.00 contract is for compound testing services, including plasma protein binding studies, PXR and AhR activation studies, and CYP inhibition assays on various small molecule compounds. This work supports NIDA's mission to seek fundamental...
- This firm-fixed-price federal contract was awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), a civilian agency within the Department of Health and Human Services (HHS), to Cyprotex US LLC, a foreign-owned, for-profit contract research organization. The $12,295.00 contract is for the provision of specialized testing services to support chemical risk assessment, drug development, and environmental research programs. Cyprotex has a significant Indefinite...
- This federal contract award provides NCATS (National Center for Advancing Translational Sciences) with testing services for 100 small molecule compounds, including CYP (cytochrome P450) inhibition testing. The $152,000.06 fixed-price purchase order was awarded to Cyprotex US LLC, a foreign-owned, for-profit contract research organization. The contract work is not set aside for small businesses. Cyprotex specializes in predictive toxicology, ADME (absorption, distribution, metabolism, and...
- The Department of Health and Human Services National Institutes of Health National Institute of Neurological Disorders and Stroke awarded a $6,338 firm fixed price purchase order to Cyprotex US LLC for ADME-TOX screening services in support of preliminary safety assessment of a new lead candidate for the agency's HER3 receptor project. Work will be performed by Cyprotex US LLC Division in Watertown, Massachusetts over a one year period concluding on August 30, 2024. The award was made using...
- Cyprotex US LLC was awarded a $28,100 firm fixed price purchase order by the Department of Health and Human Services' National Institutes of Health's National Institute on Drug Abuse to provide absorption, distribution, metabolism, and excretion testing services of drug compounds. The solicitation requested absorption, distribution, metabolism, and excretion testing including solubility, parallel artificial membrane permeability assay, microsomal stability, liquid chromatography-mass...
This firm fixed-price purchase order was awarded by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH) within the Department of Health and Human Services (HHS), to Cyprotex US LLC, a foreign-owned for-profit contract research organization. The $157,158 contract is for the characterization of absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties of small-molecule drug candidates using standardized in vitro methods. This work supports the NCI's Developmental Therapeutics Program. Cyprotex has previously provided toxicokinetic testing and other specialized services to federal agencies including the EPA, HHS, and VA. The contract has no set-aside designation.
Generated 3/21/24, 7:00 PM
Name | Description | Solicitation Number | FederalAgency | Type | PostedDate |
|---|---|---|---|---|---|
Characterization of Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) Properties of Small-molecule Drug Candidates Using Standardized In Vitro Methods | 75N91022Q00202 | Department of Health and Human Services National Institutes of Health National Cancer Institute | Solicitation 1/1 | 8/23/22, 10:41 AM |
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | Not listed | $157.2k | 9/15/22 |