Purchase Order 75N91019P00282

This firm-fixed price purchase order contract was awarded by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH) within the Department of Health and Human Services (HHS), to Expression Manufacturing LLC, a for-profit limited liability company, to provide 250 ml of concentrated lentiviral vector and conduct stability testing. The contract, valued at $648,968.00, has an ultimate completion date of August 31, 2029. This sole-source procurement was originally...

This firm fixed price purchase order, valued at $60,000, was awarded by the National Institutes of Health's National Institute of Allergy and Infectious Diseases to Leveragen Inc. of Worcester, Massachusetts. Under this contract, Leveragen will generate two lines of mice with specific CRISPR gene edits to the CTCF gene, containing either an R448Q mutation or a GRP>AAA mutation in amino acids 662-664. This work directly continues the solicitation to develop broadly neutralizing nanobodies...

The Department of Health and Human Services National Institutes of Health National Institute of Allergy and Infectious Diseases awarded a $17,450.00 firm fixed price purchase order to Applied Stemcell, Inc. to investigate cellular dysfunction associated with hereditary mutation within the prion gene. The contractor must generate two homozygous clones with the E200K prion gene mutation removed and two clones without the mutation removed, validating pluripotency and gene sequence. This requirement...

This purchase order awards Vector Biosystems, Inc., doing business as Vector Biolabs, $12,060 to deliver two custom adeno-associated viral constructs to the National Center for Advancing Translational Sciences within the Department of Health and Human Services' National Institutes of Health. Specifically, Vector Biosystems will provide one AAV6 vector containing GFP and an shRNA targeting human COLQ, and one AAV6 vector containing GFP and an shRNA targeting human DOK7. Both constructs are to...

This is a $26,650.70 firm fixed price purchase order awarded by the National Center for Advancing Translational Sciences (NCATS) to Genewiz, LLC, a subsidiary of Azenta, Inc. The contract is for custom cloning and lentiviral preparation services to support the development of assays and therapeutics for NGYL1 disease within NCATS' Therapeutic Development Branch. The work includes gene cloning, lentiviral vector preparation, and generation of lentiviral particles at high titer. This contract has...

The Department of Health and Human Services (HHS), National Institutes of Health (NIH), National Cancer Institute (NCI) awarded a purchase order contract valued at one hundred twenty thousand six hundred dollars ($120,600) to Vector Biomed Inc. The contract is to obtain preclinical grade lentiviral vectors in support of NCI's Pediatric Oncology Branch investigational new drug enabling studies and demonstration of clinical-grade vector production feasibility. Services include receipt confirmation...

The Department of Health and Human Services National Institutes of Health National Institute of Allergy and Infectious Diseases awarded a firm-fixed-price purchase order to Genscript USA Inc., a biotechnology company, for "EXPRESS PLASMID PREPARATION, EXPRESS MUTAGENESIS TARGET AND CLONEARK PLASMID PREPARATION" services. The $149,984.10 contract has a completion date of September 13, 2022 and does not have a set-aside designation. Genscript has provided similar services to support...

The Department of Health and Human Services (HHS) National Institutes of Health (NIH) Clinical Center awarded a firm-fixed-price purchase order to Sirion Biotech GMBH, a foreign-owned for-profit company, for the delivery of LENTIBOOST formulated, good manufacturing practice (GMP)-grade lentiviral products. The $21,000 contract is to support gene therapy research and patient treatments conducted by the NIH Clinical Center. The award does not include any set-aside designation or subcontractors....

The Department of Health and Human Services National Institutes of Health National Institute of Allergy and Infectious Diseases Division of Acquisitions awarded a $103,508.51 purchase order to Trenzyme GmbH of Bethesda, Maryland. The contract calls for the prime contractor to perform PCR-amplification and cloning of a tet-on inducible exoin-C/E3/E2/6K/E1 vector to support the agency's biomedical research efforts. Work will be conducted in Bethesda through January 18, 2010 under a fixed price...

The Department of the Army Medical Command awarded a $10,505 firm fixed price call against its Basic Purchasing Agreement to Trilink Biotechnologies, LLC. The contract is for the delivery of PFCSP (M) CAP1 MRNA (WT) with an anticipated completion date of April 10, 2020. As the place of performance is listed as San Diego, California, it can be inferred the products or services will be delivered within the state. No set-aside designation was specified. Trilink Biotechnologies, LLC is the prime...