Grant For Research NNX15AL13G
- Not listed
- This is a $300,000.00 federal grant awarded by the National Aeronautics and Space Administration (NASA) to Virginia Commonwealth University (VCU) to examine the effects of simulated microgravity on bone cells and bone health. The grant, which runs from July 2018 to December 2023, has two main goals: 1) to study the response of normal and genetically modified (CRISPR-edited) mouse bone cells to simulated microgravity conditions in vitro using a specialized bioreactor, and 2) to examine the impact...
- This is a sole source federal grant award from the National Aeronautics and Space Administration (NASA) to the Trustees of Indiana University, doing business as Indiana University, for a project titled "Rodent Research Standard Housing Mission: Multidisciplinary Approach to Understanding Spaceflight Responses." The $322,557.00 grant has a completion date of February 6, 2026 and supports research using rodent models to study the effects of spaceflight. Indiana University is a major...
- This is a $296,907.57 grant awarded by NASA to The Research Foundation for the State University of New York (Stony Brook University) to study the effects of microgravity and partial microgravity on bone remodeling, as well as evaluate hypergravity as a countermeasure for microgravity-induced bone loss. The objective is to understand the underlying causes of bone loss experienced by astronauts during long-duration spaceflight and develop effective countermeasures to sustain bone health, which...
- This is a $150,000.00 grant awarded by the National Aeronautics and Space Administration (NASA) to Louisiana State University (LSU) to conduct a time course study on bone microarchitectural and material property changes in male and female mice during simulated unloading and spaceflight. The grant has a period of performance ending on February 28, 2026. LSU, a major research university, is serving as the prime contractor on this grant. There is no set-aside designation associated with this award....
- This is a $733,792.00 grant awarded by the National Aeronautics and Space Administration (NASA) to the Trustees of Indiana University, doing business as Indiana University, for a research project studying the evolutionary implications of dormancy in spore-forming Bacillus and related taxa under energy limitation. The grant has a performance period ending on May 31, 2026. Indiana University is a prominent public research university with extensive expertise in areas such as biomedical sciences,...
- This is a $1,328,066.91 grant awarded by the NASA Shared Services Center to Loma Linda University, a private non-profit educational institution, to conduct an experiment protocol involving mice on the International Space Station (ISS). The experiment will study the effects of the antioxidant compound Mn(III) tetrakis (N-ethylpyridinium-2-yl) porphyrin (MnTE-2-Py) on oxidative stress, retinal endothelial cells, and extracellular matrix in microgravity. The mice will be housed on the ISS for up to...
- This is a grant awarded by the National Aeronautics and Space Administration (NASA) to Oregon State University (OSU) to study the impact of microgravity and cold stress on bone loss and immune function in mice. The $358,718 grant is intended to identify the mechanisms by which spaceflight alters the differentiation of stem cells within bone marrow, leading to bone loss, increased fat content, anemia, and impaired immune response. The research will compare the effects of hindlimb unloading...
- The National Aeronautics and Space Administration (NASA) has awarded a $298,974.04 grant to the University of Wisconsin - Madison, operating as Research and Sponsored Programs under the University of Wisconsin System, to conduct research on the effects of altered gravity on nuclear morphology and cytoskeletal organization in fibroblasts during parabolic flight. The research will involve culturing cells in specialized hardware to control temperature and humidity, fixing the cells at different...
- This federal contract award, NNX15AU64H, was issued by the Shared Services Center to Boise State University to conduct research on the effects of microgravity on bone loss and osteoporosis. The $164,997.88 training grant aims to demonstrate how mechanical unloading in microgravity triggers changes in TRPV4 calcium channel transport, leading to increased osteoclast differentiation and bone resorption. The research plan involves experiments using NASA's Rotary Cell Culture System to assess calcium...
- This federal contract award from the National Aeronautics and Space Administration (NASA) to The Research Foundation for the State University of New York (SUNY), doing business as Stony Brook University, is a $299,683.70 grant to study the effects of microgravity on the coupling and communication between osteoblasts and osteoclasts, the cells responsible for bone remodeling. The goal is to identify countermeasures, such as the use of bisphosphonates or anti-RANKL antibodies, to mitigate the...
This is a $1,999,998.00 grant awarded by the Shared Services Center of the National Aeronautics and Space Administration (NASA) to the Trustees of Indiana University, a public research university, for a project titled "Foundational In Vivo Experiments on Osteocyte Biology in Space". The purpose of the grant is to study the effects of long-term spaceflight on bone health, with a focus on understanding the biological changes in osteocytes (bone cells) and bone matrix properties that contribute to bone loss experienced by astronauts. The research will involve studying mice that have spent 5 weeks or 4 months aboard the International Space Station, using an "omics" approach to capture changes in DNA, RNA, and proteins. The goal is to elucidate new mechanisms that can be targeted to counteract space travel-induced bone loss. This grant does not have a set-aside designation.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 10/3/23 | ||
| 19 | Other Administrative Action | $0 | 10/3/23 | |
| 18 | Other Administrative Action | $0 | 9/21/22 | |
| Not listed | $0 | 9/21/22 | ||
| Not listed | $0 | 9/29/21 |