Grant For Research 80NSSC19K0431
- Not listed
- This is a $300,000.00 federal grant awarded by the National Aeronautics and Space Administration (NASA) to Virginia Commonwealth University (VCU) to examine the effects of simulated microgravity on bone cells and bone health. The grant, which runs from July 2018 to December 2023, has two main goals: 1) to study the response of normal and genetically modified (CRISPR-edited) mouse bone cells to simulated microgravity conditions in vitro using a specialized bioreactor, and 2) to examine the impact...
- This is a $1,999,998.00 grant awarded by the Shared Services Center of the National Aeronautics and Space Administration (NASA) to the Trustees of Indiana University, a public research university, for a project titled "Foundational In Vivo Experiments on Osteocyte Biology in Space". The purpose of the grant is to study the effects of long-term spaceflight on bone health, with a focus on understanding the biological changes in osteocytes (bone cells) and bone matrix properties that...
- This is a grant awarded by the National Aeronautics and Space Administration (NASA) to Oregon State University (OSU) to study the impact of microgravity and cold stress on bone loss and immune function in mice. The $358,718 grant is intended to identify the mechanisms by which spaceflight alters the differentiation of stem cells within bone marrow, leading to bone loss, increased fat content, anemia, and impaired immune response. The research will compare the effects of hindlimb unloading...
- This $949,055.36 research grant was awarded by NASA's Shared Services Center to Florida State University (FSU) to study the effects of weightlessness on the human body. The purpose is to examine how simulated microgravity impacts the structure and function of various organ systems, including the cardiovascular, lymphatic, digestive, musculoskeletal, visual, and neural systems. The research will use a rat model to contrast the adaptations induced by head-ward fluid shifts versus full or partial...
- This federal contract award, NNX15AU64H, was issued by the Shared Services Center to Boise State University to conduct research on the effects of microgravity on bone loss and osteoporosis. The $164,997.88 training grant aims to demonstrate how mechanical unloading in microgravity triggers changes in TRPV4 calcium channel transport, leading to increased osteoclast differentiation and bone resorption. The research plan involves experiments using NASA's Rotary Cell Culture System to assess calcium...
- This is a $1,010,000.00 grant awarded by the Shared Services Center of the National Aeronautics and Space Administration (NASA) to Wake Forest University Health Sciences (WFUHS) for a research project titled "Quantitative CT and MRI-Based Modeling Assessment of Dynamic Vertebral Strength and Injury Risk Following Long-Duration Spaceflight." The grant is focused on measuring the degradation of astronauts' vertebrae and spinal muscles during long-duration missions aboard the...
- This federal contract award, with ID NNX16AL36G, was granted by the National Aeronautics and Space Administration (NASA) to Beth Israel Deaconess Medical Center, Inc. (BIDMC), a non-profit academic medical center in Boston, MA. The $1,066,991.00 grant funds a research study on the musculoskeletal response of rats exposed to varying levels of partial gravity, from 0.2G to 0.7G, to better understand the impact on muscle atrophy and bone loss. This research aims to inform the development of...
- The University of California, Davis received a $651,979 research grant from a civilian federal agency (Shared Services Center) with an ultimate completion date of May 31, 2026. The award supports a research program investigating the use of artificial gravity as a countermeasure to mitigate physiological and behavioral deterioration caused by spaceflight exposure. The study employs an established mouse model and a centrifuge aboard the International Space Station (ISS) to establish...
- This federal contract award is a grant for research valued at $763,349.78 awarded to the State University of New York (SUNY) by the National Aeronautics and Space Administration (NASA). The grant is for research on the "Genetic Basis Loss of Musculo-Skeletal Tissues During Weightlessness" and has a performance period ending on July 26, 2007. The grant does not have a set-aside designation. SUNY is a prominent educational institution that provides educational support and training...
- This is a $140,000 grant awarded by the National Aeronautics and Space Administration (NASA) to Florida State University (FSU) to conduct research on the effects of long-term exposure to the microgravity environment on the cardiovascular and immune systems of astronauts. The research will utilize the hindlimb-unloading rodent model to simulate microgravity conditions and investigate changes in circulatory function, immune system responses, and the potential therapeutic effects of the...
This is a $296,907.57 grant awarded by NASA to The Research Foundation for the State University of New York (Stony Brook University) to study the effects of microgravity and partial microgravity on bone remodeling, as well as evaluate hypergravity as a countermeasure for microgravity-induced bone loss. The objective is to understand the underlying causes of bone loss experienced by astronauts during long-duration spaceflight and develop effective countermeasures to sustain bone health, which is critical for enabling future human exploration of Mars. The research will use rat suspension models to analyze bone microstructure, mechanical properties, and gene expression under simulated microgravity and partial microgravity conditions, as well as the efficacy of periodic hypergravity as a countermeasure. This work aims to fill recognized gaps in NASA's knowledge and research priorities related to mitigating the impacts of spaceflight on astronaut skeletal health.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| P0010 | Funding Only Action | ($3k) | 9/24/24 | |
| Not listed | ($3k) | 9/24/24 | ||
| P00009 | Other Administrative Action | $0 | 1/19/23 | |
| Not listed | $0 | 1/19/23 | ||
| Not listed | $0 | 12/28/21 |