DHA phase III small business innovation research prototype other transaction agreement for project titled, "broad spectrum snakebite antidote: conclusion of oral product development"

Active Other Transaction Agreement Awarded Last action

Contract number
HT94252590011
Awardee
Awarding agency
Obligated
$29,999,425

Award facts

Contract value 100% obligated
$29,999,425.00 Current and potential, with all options
Completion date 81% complete
Current and potential, with all options
NAICS code
Not on record
Competition
Competed Broad Agency Announcement
Pricing
Other
Place of performance
Corte Madera, CA 94925, USA

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Other Administrative Action P00006 $0
Supplemental Agreement for work within scope P00005 $10,815,358
Funding Only Action P00004 $12,181,539
Funding Only Action P00003 · Broad spectrum snakebite antidote: conclusion of oral product development -$3,084,480
Supplemental Agreement for work within scope P00002 · DHA phase III sbir pota for project titled "broad spectrum $0
Other Administrative Action P00001 · DHA phase III sbir pota for project titled "broad spectrum snakebite antidote: conclusion of oral product development" -$5,721,986
Original award $15,808,994

About this award

The Defense Health Agency awarded an Other Transaction Agreement to Ophirex, Inc., a small business, on May 5, 2025, with a ceiling value of $29,999,425 for Phase III development of a broad-spectrum snakebite antidote in oral formulation. This OTA sits outside the FAR and represents the concluding phase of the company's SBIR-funded effort to develop varespladib, a phospholipase A2 inhibitor targeting snake venom toxins.

The agreement runs through March 4, 2027. Work is performed at Ophirex's facility in Corte Madera, California. The oral product development effort builds on prior DHA and Army Medical Command SBIR phases and complements parallel development of an intravenous formulation supported by FDA grant funding. Varespladib is designed to improve recovery outcomes and reduce complications in snakebite envenomation cases, addressing limitations of conventional antivenom treatments.

Quick answers

Who was awarded contract HT94252590011?

HT94252590011 was awarded to Ophirex, Inc. by Defense Health Agency (Department of Defense) on May 5, 2025.

How much is contract HT94252590011 worth?

The government has obligated $29,999,425 on HT94252590011.

Was contract HT94252590011 competed?

The extent of competition for HT94252590011 was competed.

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